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Table 2 Complications and in-hospital outcomes of patients with COVID-19

From: Pre-existing cardiovascular disease rather than cardiovascular risk factors drives mortality in COVID-19

 

Total

N = 1721

No CVD or CV risk factors

N = 484 (28.1%)

RF-CVD

N = 888 (51.6%)

CVD

N = 349 (20.3%)

p value

Complications

Cardiac

 Acute myocardial infarction

68 (4.0)

4 (0.8)

21 (2.4)

43 (12.3)

 < 0.001

 Acute heart failure

151 (8.8)

12 (2.5)

43 (4.8)

96 (27.5)

 < 0.001

 Myocarditis

12 (0.7)

0

9 (1.0)

3 (0.9)

0.090

 Pericarditis

2 (0.1)

1 (0.2)

1 (0.1)

0

0.688

 Arrhythmia*

314 (18.3)

40 (8.3)

99 (11.2)

175 (50.1)

 < 0.001

  Atrial fibrillation

266 (15.5)

28 (5.8)

74 (8.3)

164 (47.0)

 < 0.001

Number of cardiac complications**

 < 0.001

 0

1,290 (75.0)

433 (89.5)

738 (83.1)

119 (34.1)

 

 1

325 (18.9)

45 (9.3)

129 (14.5)

151 (43.3)

 

 2+

106 (6.2)

6 (1.2)

21 (2.4)

79 (22.6)

 

Venous thromboembolism

 Pulmonary embolism

151 (8.8)

41 (8.5)

66 (7.4)

44 (12.6)

0.015

 Deep vein thrombosis

98 (5.7)

21 (4.3)

43 (4.8)

34 (9.7)

0.001

Extra-cardiac

 Acute kidney injury***

 ARDS

 Mechanical ventilation

266 (15.5)

77 (4.5)

92 (34.9)

30 (6.2)

19 (3.9)

36 (43.9)

164 (18.5)

46 (5.2)

41 (27.2)

72 (20.6)

12 (3.4)

15 (48.4)

 < 0.001

0.324

0.009

Outcomes

Died in hospital

438 (25.5)

80 (16.5)

228 (25.7)

130 (37.3)

 < 0.001

ICU admission

226 (13.1)

75 (15.3)

127 (14.3)

24 (6.9)

 < 0.001

Death or ICU admission

587 (34.1)

133 (27.4)

311 (35.0)

145 (41.4)

 < 0.001

Discharged from hospital alive

1,246 (72.4)

393 (81.2)

639 (72.0)

214 (61.3)

 < 0.001

 Hospital length of stay$, days

9 (4–17)

7 (3–16)

8 (4–18)

11 (5–19)

 < 0.001

  1. Data presented as n (%) or median (IQR). Table includes all in-hospital diagnoses during the admission (including new and recurrent diagnoses)
  2. *Any physician-identified cardiac arrhythmia
  3. **Number of physician-diagnosed CV complications from the following: acute myocardial infarction, heart failure, myocarditis, pericarditis, arrhythmia including AF, and endocarditis
  4. ***Acute kidney injury was defined according to the Kidney Disease: Improving Global Outcomes definition[39]
  5. $Among patients discharged[40,41,42,43]