Skip to main content
Fig. 3 | BMC Cardiovascular Disorders

Fig. 3

From: Circular RNA mmu_circ_0005019 inhibits fibrosis of cardiac fibroblasts and reverses electrical remodeling of cardiomyocytes

Fig. 3

Effect of mmu_circ_0005019 overexpression on the apoptosis and expression of transient outward potassium channel (Ito), voltage-gated sodium channel (INA) and small conductance calcium-activated potassium channel current 3 (SK3) in cardiomyocytes. A Apoptosis of cardiomyocytes transfection with mmu_circ_0005019 or vector control were determined by Annexin V-FITC staining flow cytometry (Mann–Whitney U test). n = 3. B Relative expression of Kcnd1, Kcnd3, Scn5a and Kcnn3 of cardiomyocytes transfection with mmu_circ_0005019 or vector control were determined by qRT-PCR (Student’s t-test and Mann–Whitney U test). For Scn5a after mmu_circ_0005019 transfection, n = 5; for the others, n = 3. The results are expressed as the mean ± sem. *mmu_circ_0005019 vs. vector control, P < 0.05

Back to article page