Fig. 1

Effect of mmu_circ_0005019 overexpression on the proliferation, migration, differentiation into myofibroblasts and expression of collagen in cardiac fibroblasts. A Overexpression of exogenous mmu_circ_0005019 in cardiac fibroblasts were identified by qRT-PCR (Student’s t-test). n = 3. B Growth curves of cardiac fibroblasts after transfection with mmu_circ_0005019 or vector control were examined by CCK-8 assays (Student’s t-test). n = 3. C Migration of cardiac fibroblasts transfection with mmu_circ_0005019 or vector control were determined by transwell assays (Mann–Whitney U test). n = 10. D Relative expression of Acta2, Vim, Cola1 and Col3a1 of cardiac fibroblasts transfection with mmu_circ_0005019 or vector control were determined by qRT-PCR (Student’s t-test). n = 3. The results are expressed as the mean ± sem. *mmu_circ_0005019 vs. vector control, P < 0.05