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Table 1 Baseline clinical and laboratory characteristics of different grades of SCH group

From: Characteristics of coronary artery disease in patients with subclinical hypothyroidism: evaluation using coronary artery computed tomography angiography

Characteristics SCH patients (n = 234) Mild SCH (n = 143) Moderate SCH (n = 62) Severe SCH (n = 28) p value
Age (year) 71.5 ± 9.8 72.0 ± 9.8 70.9 ± 9.4 69.9 ± 10.2 0.514
Male (%) 116 (49.6) 75 (52.4) 27 (43.5) 14 (50) 0.456
BMI (kg/m2) 23.6 ± 4.6 23.9 ± 3.1 22.8 ± 5.2 24.2 ± 8.2 0.273
Hypertension (%) 152 (65) 93 (65) 43 (69.4) 16 (57.1) 0.591
SBP (mmHg) 136.7 ± 20.3 137.7 ± 19.8 136.2 ± 21.8 132.6 ± 20.1 0.518
DBP (mmHg) 79.2 ± 13.5 79.1 ± 13.4 80.3 ± 13.3 77.4 ± 14.9 0.681
DM (%) 79 (33.8) 56 (39.2) 16 (25.8) 7 (25) 0.091
Duration of DM (year) 3.5 ± 6.9 4.1 ± 7.6 2.5 ± 5.3 2.8 ± 6.2 0.271
Hyperlipemia (%) 47 (20) 27 (18.9) 12 (19.4) 8 (28.5) 0.660
Smoking (%) 33 (14.1) 22 (15.4) 6 (9.7) 2 (7) 0.601
Using of statins (%) 39 (16.7) 28 (20.9) 7 (11.3) 4 (14.3) 0.293
Using of antiplatelet agents (%) 39 (16.7) 25 (17.5) 10 (16.1) 4 (14.3) 0.903
Fasting blood-glucose (mmol/L) 6.4 ± 2.3 6.5 ± 2.3 6.2 ± 2.4 6.4 ± 2.1 0.730
FT3 (pmol/L) 4.5 ± 2.5 4.7 ± 3.2 4.4 ± 0.8 4.1 ± 0.8 0.510
FT4 (pmol/L) 15.7 ± 2.1 16.0 ± 2.1 15.3 ± 2.1* 14.7 ± 2.0*# < 0.001
TSH (mU/L) 7.2 ± 3.1 5.5 ± 0.7 8.0 ± 0.8* 13.7 ± 4.2*# < 0.001
TG (mmol/L) 1.5 ± 0.9 1.6 ± 0.9 1.5 ± 0.8 1.5 ± 0.7 0.932
TC (mmol/L) 4.0 ± 1.0 3.9 ± 1.0 4.1 ± 1.2 4.2 ± 1.3 0.354
HDL-C (mmol/L) 1.3 ± 0.4 1.2 ± 0.4 1.3 ± 0.5 1.3 ± 0.5 0.345
LDL-C (mmol/L) 2.2 ± 0.8 2.2 ± 0.8 2.2 ± 0.9 2.4 ± 0.9 0.519
  1. *Adjusted p < 0.05 versus Mild SCH;#adjusted p < 0.05 versus Moderate SCH. BMI, body mass index; DM, diabetes mellitus; FT3, free triiodothyronine; FT4, free thyroxine; TG, triglycerides; Cho, cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol