Fig. 3

Construction of a co-expression network and key modules for HLHS. A Cluster dendrogram. B Analysis of the scale-free topology model fit index and mean connectivity for different soft threshold values. The horizontal axis is the soft threshold (power), and the vertical axis is the evaluation parameter of the scale-free network (left) or mean connectivity (right). C Gene dendrogram via average linkage hierarchical clustering. Different colors exhibit the module assignment through the dynamic tree cutting. D Heat maps showing the module-trait relationships. Each cell contains correlation coefficient and p value. Red indicates positive correlation and blue indicates negative correlation. E Eigengene adjacency heatmap. Each row and each column respectively correspond to one module eigengene. Green indicates low adjacency and red indicates high adjacency. The diagonal and red rectangle represents one meta-module. F, G KEGG pathway enrichment map and PPI network for the black and pink modules. For PPI network, the color shade of nodes is proportional to degree