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Table 3 Cox regression models for prognostic prediction, divided with the internal quantile ranges of plasma osmolality on admission

From: Prognostic relevance of elevated plasma osmolality on admission in acute decompensated heart failure with preserved ejection fraction: insights from PURSUIT-HFpEF registry

 

Unadjusted HR (95% CI)

P-value

Composite endpoint

  

Q2 versus Q1

1.13 (0.80–1.60)

1.0000

Q3 versus Q1

1.61 (1.16–2.23)

0.0120

Q3 versus Q2

1.42 (1.03–1.96)

0.0954

Cardiac mortality

  

Q2 versus Q1

0.85 (0.42–1.66)

1.0000

Q3 versus Q1

1.59 (0.89–2.88)

0.3531

Q3 versus Q2

1.88 (1.01–3.61)

0.1338

HF re-admission

  

Q2 versus Q1

1.12 (0.79–1.60)

1.0000

Q3 versus Q1

1.50 (1.08–2.11)

0.0504

Q3 versus Q2

1.34 (1.08–2.11)

0.2454

  1. HF, heart failure; HR, hazard ratio; Q1, plasma osmolality on admission < 293.2 mOsm/kg; Q2, plasma osmolality on admission ≥ 293.2 and < 300.3 mOsm/kg; and Q3, plasma osmolality on admission ≥ 300.3 mOsm/kg
  2. Cox proportional hazard models for composite endpoint, cardiac mortality and heart failure re-admission. Composite endpoint was defined as cardiac mortality or heart failure re-admission. P-value was corrected with Bonferroni adjustment
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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