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Table 3 Comparison between the malignancy and non-malignancy groups

From: Impact of pericardial fluid glucose level and computed tomography attenuation values on diagnosis of malignancy-related pericardial effusion

Serum component

Malignancy group

Non-malignancy group

p

CRP (mg/dl)

5.33 ± 4.37

4.54 ± 6.70

0.488

eGFR (ml/min/1.73 m2)

60.56 ± 31.42

45.97 ± 29.08

0.024

Total protein (g/dl)

6.08 ± 0.60

6.06 ± 1.27

0.889

LDH (U/L)

543.35 ± 767.60

357.98 ± 186.54

0.138

Albumin (g/dl)

3.01 ± 0.46

3.11 ± 0.75

0.399

Glucose (mg/dl)

142.20 ± 61.03

134.10 ± 53.05

0.518

Hemoglobin (g/dl)

11.01 ± 1.77

11.11 ± 1.60

0.766

Hematocrit (%)

33.29 ± 5.61

34.24 ± 4.84

0.391

BNP (pg/ml)

126.89 ± 183.35

409.18 ± 868.67

0.037

Pericardial fluid component

   

Ph

7.39 ± 0.20

7.48 ± 0.12

0.069

Total protein (g/dl)

5.02 ± 0.80

4.72 ± 1.19

0.166

LDH (U/L)

2032.10 ± 3522.33

1029.58 ± 1561.52

0.106

Albumin (g/dl)

2.66 ± 0.53

2.61 ± 0.70

0.661

Glucose (mg/dl)

78.24 ± 48.29

98.41 ± 44.85

0.048

ADA (U/L)

37.59 ± 47.26

29.34 ± 37.66

0.389

Hyaluronic acid (ng/ml)

31,975.9 ± 27,282.7

27,194.6 ± 28,745.9

0.438

Hemoglobin (g/dl)

3.83 ± 2.22

5.15 ± 5.19

0.422

Hematocrit (%)

14.79 ± 6.73

16.74 ± 21.36

0.788

Variable

   

Pericardial fluid/serum ratio

   

 Total protein ratio

0.83 ± 0.14

0.78 ± 0.15

0.127

 LDH ratio

5.23 ± 7.69

2.59 ± 2.71

0.047

 Glucose ratio

0.57 ± 0.34

0.83 ± 0.45

0.005

Pericardial fluid/Serum total protein ratio > 0.5

49 (100%)

38 (97.4%)

0.260

Pericardial fluid/Serum LDH ratio > 0.6

47 (94.0%)

29 (76.3%)

0.017

Pericardial fluid LDH > 2/3 UNL

49 (98.0%)

32 (86.5%)

0.036

Cytology, positive

43 (76.8%)

 − 

 − 

  1. Lower serum BNP and lower pericardial fluid glucose level were associated with malignancy
  2. Values are expressed as mean ± standard deviation
  3. CRP C-reactive protein, eGFR estimated glomerular filtration rate, LDH lactate dehydrogenase, BNP brain natriuretic protein, ADA adenosine deaminase, UNL upper limit of normal