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Table 4 Results of multiple linear regression analysis associated with SS values with adjustment for generally known cardiovascular risk factors and ER2 gene polymorphisms (rs1256049 and rs4986938)

From: The association between estrogen receptor 2 gene polymorphism and complexity of coronary artery disease: an analysis in elective percutaneous coronary intervention patients

Independent variables

Women (n = 38)

Men (n = 110)

Standardized β

95% C.I

Standardized β

95% C.I

Age

0.17

(− 0.25, 0.77)

0.07

(− 0.14, 0.26)

GFR (MDRD)

0.33

(− 0.01, 0.33)

0.03

(− 0.06, 0.09)

BUN

0.45

(0.15, 1.24)

0.14

(− 0.06, 0.64)

DM

− 0.19

(− 12.29, 2.12)

− 0.02

(− 4.30, 3.47)

Hypertension

− 0.09

(− 12.82, 7.71)

− 0.11

(− 5.98, 1.34)

Hyperlipidemia

0.16

(− 3.09, 11.97)

0.14

(− 0.74, 6.93)

Smoking

0.42

(− 10.97, 14.73)

0.09

(− 1.45, 5.43)

Number of diseased vessels

0.30

(− 2.87, 12.72)

0.36

(2.39, 7.82)

MVD

− 0.38

(− 23.63, 2.9)

− 0.19

(− 8.39, 0.26)

Sever CAD

0.14

(− 17.55, 7.53)

− 0.14

(− 8.69, 0.91)

rs1256049

    

AA (reference)

    

  AG

NA

NA

0.22

(− 10.89, 25.83)

  GG

− 0.14

(− 22.25, 7.97)

− 0.02

(− 18.51, 17.40)

rs4986938

    

AA (reference)

    

  AG

− 0.09

(− 17.00, 12.00)

0.27

(0.08, 12.21)

  GG

− 0.17

(− 19.17, 9.73)

0.28

(0.02, 12.15)

  1. GFR glomerular filtration rate, BUN blood urea nitrogen, DM diabetes mellitus, CAD coronary artery disease, MVD multi-vessel disease, NA not assigned