Table 3 Associations of sex and SYNTAX score with ER2 gene polymorphisms in patients with CAD
Receptor gene | SYNTAX score | p value | Gender | p value | ||
|---|---|---|---|---|---|---|
˂23 (n = 109) | ≥ 23 (n = 41) | Men (n = 110) | Women (n = 38) | |||
rs4986938, N (%) | ||||||
GG | 58 (53.2) | 25 (61) | 0.16 | 61 (54.5) | 22 (57.9) | 0.9 |
AG | 37 (33.9) | 15 (36.6) | 40 (35.7) | 12 (31.6) | ||
AA | 14 (12.8) | 1 (2.4) | 11 (9.8) | 4 (10.5) | ||
Alleles, N (%) | ||||||
A | 63 (28.9) | 19 (23.2) | 0.32 | 64 (28.6) | 18 (23.7) | 0.41 |
G | 155 (71.1) | 63 (76.8) | 160 (71.4) | 58 (76.3) | ||
rs1256049, N (%) | ||||||
GG | 101 (92.7) | 32 (78) | 0.01 | 98 (87.5) | 35 (92.1) | 0.82* |
AG | 7 (6.4) | 9 (22) | 13 (11.6) | 3 (7.9) | ||
AA | 1 (0.9) | 0 (0) | 1 (0.9) | 0 (0) | ||
Alleles, N (%) | ||||||
A | 9 (4.1) | 9 (11) | 0.05 | 15 (6.7) | 3 (3.9) | 0.53 |
G | 209 (95.9) | 73 (89) | 209 (93.3) | 73 (96.1) | ||