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Table 6 Sensitivity of native T1, ECV using synthetic hematocrit at mid LV and combination (native T1 followed by ECV if T1 was normal) in the disgnosis of amyloidosis, dilated cardiomyopathy (DCM0, hypertrophic cardiomyopathy (HCM), myocarditis, and coronary artery disease (CAD). P-values of comparison of combination of test and single test based on McNemar’s test are shown

From: Native T1 mapping and extracellular volume fraction for differentiation of myocardial diseases from normal CMR controls in routine clinical practice

Test Amyloidosis
(n = 11)
DCM
(n = 157)
HCM
(n = 112)
Myocarditis
(n = 17)
CAD
(n = 293)
1 Native T1 11 (100%) 88 (56.1%) 60 (53.6%) 7 (41.2%) 90 (30.7%)
2 ECV synthetic 9 (81.8%) 114 (72.6%) 52 (46.4%) 7 (41.2%) 158 (53.9%)
3 T1 and ECV synthetic 11 (100.0%) 125 (79.6%) 60 (53.6%) 7 (41.2%) 175 (59.7%)
1 vs. 3 P-value < 0.001 1.000 1.000 < 0.001
2 vs. 3 P-value 0.001 0.229 1.000 < 0.001