Table 4 Cutoff values from receiver operating characteristic (ROC) curve analysis of native T1 in myocardial disease and CAD
| Â | Cutoff (ms) | AUC | p-value | Specificity (%) (95% CI) | Sensitivity (%) (95% CI) | PPV (%) (95% CI) | NPV (%) (95% CI) | Diagnostic Accuracy (%) (95% CI) |
|---|---|---|---|---|---|---|---|---|
Amyloidosis (n = 11) | ||||||||
Mid LV short-axis native T1 | 1,341 | 0.990 | < 0.001 | 93.9 (91.7–95.6) | 100 (74.1–100.0) | 23.4 (13.6–37.2) | 100 (99.3–100) | 94.1 (91.9–95.7) |
Septum native T1 | 1,370 | 0.936 | < 0.001 | 99.7 (98.8–99.9) | 81.8 (52.3–94.9) | 81.8 (52.3–94.9) | 99.7 (98.8–99.9) | 99.3 (98.3–99.7) |
DCM (n = 157) | ||||||||
Mid LV short-axis native T1 | 1,338 | 0.783 | < 0.001 | 90.9 (88.3–93.3) | 56.1 (48.2–63.6) | 62.0 (53.8–69.5) | 88.7 (85.9–91.0) | 83.6 (80.8–86.1) |
Septum native T1 | 1,341 | 0.736 | < 0.001 | 94.3 (92.1–95.9) | 50.3 (42.6–58.0) | 69.9 (60.9–77.6) | 87.8 (85.0–90.1) | 85.1 (82.4–87.5) |
HCM (n = 112) | ||||||||
Mid LV short-axis native T1 | 1,333 | 0.723 | < 0.001 | 86.9 (83.9–89.4) | 53.6 (44.4–62.5) | 43.5 (35.5–51.8) | 90.9 (88.2–93.0) | 81.6 (78.6–84.3) |
Septum native T1 | 1,346 | 0.711 | < 0.001 | 96.0 (94.1–97.3) | 40.2 (31.6–49.4) | 65.2 (53.4–75.4) | 89.5 (86.9–91.6) | 87.1 (84.5–89.4) |
Myocarditis (n = 17) | ||||||||
Mid LV short-axis native T1 | 1,355 | 0.710 | 0.003 | 98.3 (96.9–99.1) | 41.2 (21.6–64.0) | 41.2 (21.6–64.0) | 98.3 (96.9–99.1) | 96.7 (95.0–97.9) |
Septum native T1 | 1,360 | 0.752 | < 0.001 | 99.2 (98.0–99.6) | 35.3 (17.3–58.7) | 54.5 (28.0–78.7) | 98.2 (96.8–99.0) | 97.4 (95.8–98.4) |
CAD | ||||||||
Mid LV short-axis native T1 (n = 293) | 1,342 | 0.621 | < 0.001 | 94.3 (92.1–95.9) | 30.7 (25.7–36.2) | 72.6 (64.1–79.7) | 73.4 (70.2–76.4) | 73.3 (70.3–76.1) |
Septum native T1 (n = 247) | 1,343 | 0.618 | < 0.001 | 94.6 (92.5–96.2) | 28.7 (23.5–34.7) | 68.9 (59.4–77.1) | 76.2 (73.0–79.1) | 75.3 (72.3–78.1) |