Plasma uric acid is related to large arterial stiffness but not to other hemodynamic variables: a study in 606 normotensive and never-medicated hypertensive subjects

Table 3 Significant explanatory variables for aortic systolic and diastolic blood pressure in linear regression analysis with stepwise elimination

Systolic blood pressure (mmHg)	B	Beta	p	Diastolic blood pressure (mmHg)	B	Beta	p
R² = 0.399				R² = 0.350
(constant)	− 24.905			(constant)	− 23.172
Lg₁₀ of pulse wave velocity	81.312	0.384	< 0.001	Lg₁₀ of pulse wave velocity	47.287	0.333	< 0.001
eGFR	− 0.188	− 0.174	< 0.001	Calcium	20.013	0.159	< 0.001
Calcium	23.794	0.127	< 0.001	PTH	1.013	0.128	0.001
PTH	1.248	0.106	0.003	eGFR	− 0.115	− 0.159	< 0.001
LDL	3.173	0.150	< 0.001	Lg₁₀ of QUICKI	− 34.464	− 0.127	0.001
Lg₁₀ of QUICKI	− 40.982	− 0.102	0.007	High alcohol consumption category	7.565	0.083	0.020
Lg₁₀ of triglycerides	− 7.905	− 0.091	0.030	Sex (male)	2.103	0.080	0.029

Variables in Model: Age, sex, body mass index, alcohol consumption category (low, moderate, high), smoking status (current, previous); plasma uric acid, sodium, calcium, phosphate, PTH, HDL cholesterol, LDL cholesterol, eGFR; Lg₁₀ of triglycerides, C-reactive protein, renin, aldosterone, QUICKI, pulse wave velocity. LDL low-density lipoprotein, HDL high-density lipoprotein, QUICKI quantitative insulin sensitivity check index, PTH parathyroid hormone, eGFR estimated glomerular filtration rate from plasma cystatin-C using the CKD-EPI formula [15]

ISSN: 1471-2261