Fig. 2
From: KLK11 promotes the activation of mTOR and protein synthesis to facilitate cardiac hypertrophy
KLK11 expression is upregulated in murine hypertrophic hearts. a Fraction shortening and the ejection fraction of control and hypertrophic hearts in mice (n = 5). Cardiac hypertrophy in C57BL/6 mice was induced by TAC surgery for four weeks. **P < 0.01 by unpaired Student’s t test. b Heart weight of control and hypertrophic hearts in mice (n = 5). Cardiac hypertrophy in C57BL/6 mice was induced by TAC surgery for four weeks. HW, heart weight; BW, body weight; TL, tibia length. **P < 0.01 by unpaired Student’s t test. c Expression of mRNA of ANP, BNP, and MYH7 in control and hypertrophic heart tissues in mice (n = 5). Cardiac hypertrophy in C57BL/6 mice was induced by TAC surgery for four weeks. ANP, atrial natriuretic peptide; BNP, brain natriuretic peptide; MYH7, β-myosin heavy chain; **P < 0.01 vs Sham by unpaired Student’s t test. d Expression of mRNA of KLK11 in control and hypertrophic heart tissues in mice (n = 5). Cardiac hypertrophy in C57BL/6 mice was induced by TAC surgery for four weeks. **P < 0.001 by unpaired Student’s t test. e Expression of protein of KLK11 in control and hypertrophic heart tissues in mice (n = 3). Cardiac hypertrophy in C57BL/6 mice was induced by TAC surgery for four weeks. **P < 0.001 by unpaired Student’s t test