Fig. 5

MiR-641 hindered ox-LDL-induced cell proliferation, migration and invasion via interacting with STIM1. a, d The impacts between miR-641 and STIM1 overexpression on STIM1, PCNA, Ki-67 and p-FAK protein expression under ox-LDL treatment were detected by western blot analysis in VSMCs. b, c The impacts between miR-641 mimic and STIM1 overexpression on cell proliferation under ox-LDL treatment were revealed by cell colony formation and DNA content quantitation assays in VSMCs. e, f The impacts between miR-641 and STIM1 overexpression on cell migration under ox-LDL treatment were investigated by wound-healing and transwell migration assays in VSMCs. g The effects between miR-641 mimic and STIM1 overexpression on cell invasion under ox-LDL treatment were revealed by transwell invasion assay in VSMCs. *P < 0.05