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Fig. 2 | BMC Cardiovascular Disorders

Fig. 2

From: Long non-coding RNA MIAT regulates ox-LDL-induced cell proliferation, migration and invasion by miR-641/STIM1 axis in human vascular smooth muscle cells

Fig. 2

MIAT regulated ox-LDL-mediated VSMC processes. a The impacts between ox-LDL treatment and MIAT silencing on MIAT expression were revealed by qRT-PCR in VSMCs. b, c The effects between ox-LDL treatment and MIAT silencing on the proliferation of VSMCs were determined by cell colony formation and DNA content quantitation assays. d, e Western blot analysis was conducted to determine the impacts between ox-LDL treatment and MIAT absence on the protein expression of PCNA, Ki-67 and p-FAK. f, g Wound-healing and transwell migration assays were employed to explain the impacts between ox-LDL treatment and MIAT knockdown on the migration of VSMCs. h The impacts between ox-LDL treatment and MIAT knockdown on the invasion of VSMCs were demonstrated by transwell invasion assay. *P < 0.05

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BMC Cardiovascular Disorders

ISSN: 1471-2261

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