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Table 1 Baseline clinical characteristics of patients

From: Appropriate intraprocedural initial heparin dosing in patients undergoing catheter ablation for atrial fibrillation receiving uninterrupted non-vitamin-K antagonist oral anticoagulant treatment

 

NG110 (n = 49)

NG120 (n = 50)

NG130 (n = 50)

WG (n = 38)

p

Age (years)

59 ± 10

63 ± 8

61 ± 7

63 ± 8

0.224

Male

27 (55.1%)

36 (72%)

32 (64%)

21 (55.3%)

0.269

Weight (kg)

76 ± 13

74 ± 9

73 ± 9

68 ± 11

0.016

Nonparoxysmal AF

21 (42.9%)

19 (38%)

14 (28%)

26 (68.4%)

0.002

Coronary artery disease

10 (20.4%)

7 (14%)

4 (8%)

8 (21.1%)

0.259

Hypertension

24 (49%)

23 (46%)

28 (56%)

18 (47.4%)

0.763

Diabetes mellitus

6 (12.2%)

8 (16%)

10 (20%)

7 (18.4)

0.754

Heart failure

5 (10.2%)

2 (4%)

2 (4%)

5 (13.2)

0.257

Stroke/TIAs

4 (8.2%)

3 (6%)

4 (8%)

4 (10.5%)

0.896

CHADS2 score

0.9 ± 0.8

0.8 ± 0.8

0.9 ± 0.8

0.9 ± 0.9

0.855

0

19 (38.8%)

21 (42%)

19 (38%)

15 (39.5%)

0.863

1

18 (36.7%)

20 (40%)

18 (36%)

11 (28.9%)

 

≥ 2

12 (24.5%)

9 (18%)

13 (26%)

12 (31.6%)

 

CHA2DS2-VASc score

1.8 ± 1.2

1.7 ± 1.3

1.7 ± 1.2

2.1 ± 1.6

0.429

HAS-BLED score

0.9 ± 0.9

0.9 ± 0.8

0.9 ± 0.7

1.0 ± 0.9

0.941

LAD (mm)

40 ± 6

41 ± 5

41 ± 6

42 ± 6

0.338

LVD (mm)

40 ± 6

47 ± 4

47 ± 4

46 ± 6

0.000

LVEF (%)

55 ± 9

57 ± 5

56 ± 5

55 ± 8

0.433

BNP (pg/mL)

176.6 ± 220.2

316.7 ± 396.8

179.9 ± 166.8

597.6 ± 753.2

0.261

Ccr (mL/min)

99 ± 19

93 ± 18

90 ± 23

90 ± 19

0.118

INR

1.1 ± 0.2

1.0 ± 0.1

1.0 ± 0.1

2.2 ± 0.9

0.000

TTR (%)

0

0

0

63.16

0.000

Thrombocyte (109/L)

187 ± 47

203 ± 45

205 ± 49

206 ± 64

0.246

Hemoglobin (g/L)

145 ± 18

148 ± 18

145 ± 18

140 ± 17

0.218

Leukocyte (109/L)

6.2 ± 1.6

6.4 ± 1.7

6.1 ± 1.5

5.9 ± 1.8

0.564

TG (mmol/L)

1.3 ± 0.6

1.5 ± 0.7

1.8 ± 1.8

1.7 ± 1.7

0.376

HDL (mmol/L)

1.2 ± 0.3

1.1 ± 0.2

1.2 ± 0.3

1.1 ± 0.2

0.084

LDL (mmol/L)

2.5 ± 1.5

2.3 ± 0.7

2.5 ± 0.6

2.3 ± 0.7

0.703

TC (mmol/L)

4.4 ± 1.0

4.3 ± 0.9

4.7 ± 1.0

4.3 ± 0.9

0.211

Anticoagulants (n)

    

0.619

 Dabigatran

13 (26.5%)

18 (36%)

17 (34%)

0 (0)

 

 Rivaroxaban

36 (73.5%)

32 (64%)

33 (66%)

0 (0)

 

Procedure time (min)

140 ± 42

131 ± 39

132 ± 38

138 ± 34

0.582

 X-ray dose (msv)

9 ± 4

10 ± 3

11 ± 5

13 ± 11

0.186

Ablation time (min)

104 ± 37

99 ± 31

99 ± 34

104 ± 32

0.779

  1. TIAs transient ischemic attacks, LAD left atrial diameter, LVD left ventricular diameter, LVEF left ventricular ejection fraction, BNP brain natriuretic peptide, Ccr creatinine clearance rate, INR international normalized ratio, TTR time in range, TG triglyceride, HDL high density lipoprotein, LDL low density lipoprotein, TC total cholesterol