Table 1 Baseline variables according to the plasma furin tertile of AMI patients
From: The association between plasma furin and cardiovascular events after acute myocardial infarction
| Â | Â | Plasma furin (pg/mL) | P value | ||
|---|---|---|---|---|---|
|  | Overall |  ≤ 117.5 | 117.5–200 |  ≥ 200 | |
Patients, n | 1100 | 356 | 374 | 370 | Â |
Anterior MI, n (%) | 313 (29.6%) | 100 (29.1%) | 116 (32.4%) | 97 (27.2%) | 0.300 |
STEMI, n (%) | 747 (69.6%) | 231 (66.8%) | 256 (70.7%) | 260 (72.2%) | 0.265 |
Age, year | 61.0 (13.4) | 60.8 (13.8) | 61.6 (13.0) | 60.7 (13.4) | 0.489 |
Male, n (%) | 817 (77.0%) | 262 (75.9%) | 275 (76.6%) | 280 (78.4%) | 0.718 |
Current smoker, n (%) | 370 (41.9%) | 127 (44.1%) | 116 (38.5%) | 127 (34.1%) | 0.345 |
Medical history, n (%) | Â | Â | Â | Â | Â |
Diabetes mellitus | 394 (37.1%) | 122 (35.7%) | 140 (38.8%) | 132 (36.9%) | 0.690 |
Hypertension | 456 (43.2%) | 150 (44.0%) | 159 (44.5%) | 147 (41.2%) | 0.624 |
MI | 45 (4.1%) | 14 (3.9%) | 13 (3.5%) | 18 (4.9%) | 0.623 |
CKD | 20 (1.9%) | 8 (2.4%) | 7 (2.0%) | 5 (1.4%) | 0.654 |
AF | 10 (0.9%) | 4 (1.1%) | 4 (1.1%) | 2 (0.5%) | 0.648 |
LIPID | 121 (11.0%) | 40 (11.2%) | 38 (10.2%) | 43 (11.6%) | 0.828 |
HF | 5 (0.5%) | 4 (1.1%) | 0 (0.0%) | 1 (0.3%) | 0.090 |
Clinical assessment | Â | Â | Â | Â | Â |
BMI (kg/m2) | 25.3 (3.6) | 25.4 (3.8) | 25.5 (3.7) | 24.9 (3.3) | 0.079 |
HBA1C (%) | 6.7 (1.6) | 6.7 (1.6) | 6.8 (1.6) | 6.6 (1.6) | 0.465 |
Glucose (mmol/L) | 8.5 (3.9) | 8.3 (3.5) | 8.4 (4.0) | 8.7 (4.3) | 0.944 |
Cr (µmol/L) | 78.5 (68.0, 94.7) | 79.1 (67.6, 95.6) | 78.1 (67.6, 93.9) | 78.0 (68.7, 93.8) | 0.912 |
LVEF (%) | 50.5 (9.0) | 51.0 (9.0) | 50.1 (9.3) | 50.5 (8.7) | 0.509 |
cTNT (pg/mL) | 1.8 (0.5, 4.9) | 1.4 (0.4, 3.9) | 1.7 (0.5, 4.6) | 2.1 (0.6, 6.2) | 0.016 |
NT-proBNP (pg/mL) | 1566(668, 3929) | 1427 (610, 3490) | 1587 (712, 4098) | 1645 (709, 4049) | 0.361 |
HR | 77.6 (14.9) | 76.5 (13.5) | 77.3 (14.2) | 78.8 (16.7) | 0.591 |
CHOL (mmol/L) | 4.3 (1.1) | 4.2 (1.1) | 4.4 (1.1) | 4.2 (1.1) | 0.601 |
TRIG (mmol/L) | 1.3 (0.9, 1.8) | 1.3 (0.9, 1.8) | 1.3 (1.0, 1.9) | 1.3 (0.9, 1.8) | 0.453 |
LDL (mmol/L) | 2.7 (0.9) | 2.6 (0.9) | 2.7 (1.0) | 2.7 (0.9) | 0.588 |
HDL (mmol/L) | 1.1 (0.3) | 1.1 (0.3) | 1.1 (0.3) | 1.1 (0.3) | 0.771 |
AST (U/L) | 45.6 (24.5, 108.3) | 42.1 (24.3, 91.1) | 43.9 (24.4, 100.3) | 52.0 (26.6, 132.7) | 0.112 |
ALT (U/L) | 30.8 (19.6, 52.5) | 31.6 (19.4, 51.7) | 30.7 (19.7, 51.1) | 31.1 (19.6, 55.1) | 0.898 |
GGT (U/L) | 29.1 (19.3, 47.9) | 28.4 (19.3, 48.5) | 28.9 (19.3, 47.1) | 29.7 (19.4, 51.0) | 0.772 |
PT (s) | 14.1 (2.0) | 14.0 (2.1) | 14.0 (1.3) | 14.3 (2.3) | 0.114 |
APTT (s) | 39.4 (35.3, 46.8) | 38.8 (35.3, 45.6) | 39.3 (35.1, 45.9) | 39.9 (35.4, 51.5) | 0.304 |
DDIMER (ng/L) | 0.4 (0.3, 0.8) | 0.4 (0.3, 0.8) | 0.4 (0.3, 0.8) | 0.4 (0.3, 0.9) | 0.653 |
Medications, n (%) | Â | Â | Â | Â | Â |
Aspirin | 1021 (96.3%) | 334 (97.1%) | 347 (96.7%) | 340 (95.2%) | 0.392 |
ACEI/ARB | 434 (40.9%) | 146 (42.4%) | 158 (44.0%) | 130 (36.4%) | 0.093 |
Statin | 1033 (97.5%) | 338 (98.3%) | 351 (97.8%) | 344 (96.4%) | 0.251 |
Diuretic | 572 (52.0%) | 186 (52.2%) | 193 (51.6%) | 193 (52.2%) | 0.996 |
Cablocker | 121 (11.0%) | 45 (12.6%) | 41 (11.0%) | 35 (9.5%) | 0.394 |
Betablocker | 528 (48.0%) | 187 (52.5%) | 178 (47.6%) | 163 (44.1%) | 0.070 |
GLP1 | 22 (2.0%) | 6 (1.7%) | 8 (2.1%) | 8 (2.2%) | 0.875 |
Insulin | 531 (48.3%) | 158 (44.4%) | 182 (48.7%) | 191 (51.6%) | 0.146 |
DPP4 | 49 (4.5%) | 15 (4.2%) | 16 (4.3%) | 18 (4.9%) | 0.895 |