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Table 1 Demographic, laboratory and haemodynamic variables

From: Coronary microvascular dysfunction is associated with degree of anaemia in end‐stage renal disease

  CFVR < 2 (n = 7) CFVR ≥ 2 (n = 15) p value
Demographics
 Age (years) 47 ± 15 55 ± 10 0.177
 Male n (%) 3 (43) 8 (53) 1.0
 Caucasian n (%) 5 (71) 12 (80) 1.0
 BMI (kg/m2) 26.3 ± 4.4 27.7 ± 4.9 0.527
 Smoker n (%)—Ex
 Never
 Current
1 (14)
6 (86)
0 (0)
4 (27)
10 (67)
1 (6)
0.744
 Hypertension n (%) 6 (86) 14 (93) 1.0
 Hypercholesterolaemia n (%) 4 (57) 11 (73) 0.630
 Peritoneal dialysis n (%) 5 (71) 9 (60) 1.0
 Duration of dialysis (months) 5 (4–48) 6 (4–9) 0.797
 ACE inhibitor n (%) 1 (14) 4 (27) 1.0
 ARB n (%) 1 (14) 3 (20) 1.0
 Statin n (%) 1 (14) 8 (53) 0.165
 Loop diuretic n (%) 5 (71) 5 (33) 0.172
 Calcium channel blocker n (%) 5 (71) 9 (60) 1.0
 Beta blocker n (%) 2 (29) 3 (20) 1.0
 Alpha blocker 3 (43) 4 (27) 0.630
 Erythropoietin treatment n (%) 5 (71) 4 (27) 0.074
Laboratory data
 Haemoglobin (g/L) 102 ± 12 117 ± 11 0.008
 Haematocrit (%) 31.2 ± 3.3 35.4 ± 3.7 0.019
 Mean cell volume (fl.) 88.9 ± 3.3 91.6 ± 3.7 0.118
 Urea (mmol/L) 21.8 ± 6.2 22.1 ± 5.6 0.902
 Creatinine (µmol/L) 673 ± 300 606 ± 192 0.534
 ACR (mg/mmol) 204 (109.3-277.8) 77.4 (62.8-199.4) 0.239
 Iron (µmol/L) 11.8 (9.5–13) 12.9 (9.4–16) 0.494
 Transferrin (g/L) 1.92 ± 0.54 2.06 ± 0.4 0.525
 Albumin (g/L) 35 ± 6 40 ± 7 0.125
 Corrected calcium (mmol/L) 2.45 ± 0.13 2.33 ± 0.17 0.123
 hsCRP (mg/L) 1.9 (1-3.6) 2.8 (1.9-8) 0.312
 NT pro-BNP (ng/L) 1900 (522–4597) 441 (342–643) 0.416
 Phosphate (mmol/L) 1.71 (1.55–2.07) 1.59 (1.53–1.69) 0.312
 PTH (µmol/L) 41.7 ± 23.2 30.5 ± 16.9 0.271
 Total cholesterol (mmol/L) 4.8 ± 1.7 5.0 ± 1.4 0.772
Haemodynamic data
 Systolic BP (mmHg) 129 ± 25 137 ± 20 0.398
 Diastolic BP (mmHg) 83 ± 14 85 ± 8 0.798
 Heart Rate (bpm) 72 ± 14 66 ± 8 0.156
  1. Data are presented as mean ± SD or median (IQR). Variables highlighted in bold demonstrated a significant difference between the two groups
  2. CFVR, coronary flow velocity reserve; BMI, body mass index; ACE, angiotensin converting enzyme; ARB, angiotensin receptor blocker; ACR, albumin creatinine ratio; hsCRP, high sensitivity C reactive peptide; NT-proBNP, N terminal pro brain natriuretic peptide; PTH, parathyroid hormone; BP, blood pressure; bpm, beats per minute