From: Coronary microvascular dysfunction is associated with degree of anaemia in end‐stage renal disease
CFVR < 2 (n = 7) | CFVR ≥ 2 (n = 15) | p value | |
---|---|---|---|
Demographics | |||
Age (years) | 47 ± 15 | 55 ± 10 | 0.177 |
Male n (%) | 3 (43) | 8 (53) | 1.0 |
Caucasian n (%) | 5 (71) | 12 (80) | 1.0 |
BMI (kg/m2) | 26.3 ± 4.4 | 27.7 ± 4.9 | 0.527 |
Smoker n (%)—Ex Never Current | 1 (14) 6 (86) 0 (0) | 4 (27) 10 (67) 1 (6) | 0.744 |
Hypertension n (%) | 6 (86) | 14 (93) | 1.0 |
Hypercholesterolaemia n (%) | 4 (57) | 11 (73) | 0.630 |
Peritoneal dialysis n (%) | 5 (71) | 9 (60) | 1.0 |
Duration of dialysis (months) | 5 (4–48) | 6 (4–9) | 0.797 |
ACE inhibitor n (%) | 1 (14) | 4 (27) | 1.0 |
ARB n (%) | 1 (14) | 3 (20) | 1.0 |
Statin n (%) | 1 (14) | 8 (53) | 0.165 |
Loop diuretic n (%) | 5 (71) | 5 (33) | 0.172 |
Calcium channel blocker n (%) | 5 (71) | 9 (60) | 1.0 |
Beta blocker n (%) | 2 (29) | 3 (20) | 1.0 |
Alpha blocker | 3 (43) | 4 (27) | 0.630 |
Erythropoietin treatment n (%) | 5 (71) | 4 (27) | 0.074 |
Laboratory data | |||
Haemoglobin (g/L) | 102 ± 12 | 117 ± 11 | 0.008 |
Haematocrit (%) | 31.2 ± 3.3 | 35.4 ± 3.7 | 0.019 |
Mean cell volume (fl.) | 88.9 ± 3.3 | 91.6 ± 3.7 | 0.118 |
Urea (mmol/L) | 21.8 ± 6.2 | 22.1 ± 5.6 | 0.902 |
Creatinine (µmol/L) | 673 ± 300 | 606 ± 192 | 0.534 |
ACR (mg/mmol) | 204 (109.3-277.8) | 77.4 (62.8-199.4) | 0.239 |
Iron (µmol/L) | 11.8 (9.5–13) | 12.9 (9.4–16) | 0.494 |
Transferrin (g/L) | 1.92 ± 0.54 | 2.06 ± 0.4 | 0.525 |
Albumin (g/L) | 35 ± 6 | 40 ± 7 | 0.125 |
Corrected calcium (mmol/L) | 2.45 ± 0.13 | 2.33 ± 0.17 | 0.123 |
hsCRP (mg/L) | 1.9 (1-3.6) | 2.8 (1.9-8) | 0.312 |
NT pro-BNP (ng/L) | 1900 (522–4597) | 441 (342–643) | 0.416 |
Phosphate (mmol/L) | 1.71 (1.55–2.07) | 1.59 (1.53–1.69) | 0.312 |
PTH (µmol/L) | 41.7 ± 23.2 | 30.5 ± 16.9 | 0.271 |
Total cholesterol (mmol/L) | 4.8 ± 1.7 | 5.0 ± 1.4 | 0.772 |
Haemodynamic data | |||
Systolic BP (mmHg) | 129 ± 25 | 137 ± 20 | 0.398 |
Diastolic BP (mmHg) | 83 ± 14 | 85 ± 8 | 0.798 |
Heart Rate (bpm) | 72 ± 14 | 66 ± 8 | 0.156 |