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Table 1 Demographic, laboratory and haemodynamic variables

From: Coronary microvascular dysfunction is associated with degree of anaemia in end‐stage renal disease

 

CFVR < 2 (n = 7)

CFVR ≥ 2 (n = 15)

p value

Demographics

 Age (years)

47 ± 15

55 ± 10

0.177

 Male n (%)

3 (43)

8 (53)

1.0

 Caucasian n (%)

5 (71)

12 (80)

1.0

 BMI (kg/m2)

26.3 ± 4.4

27.7 ± 4.9

0.527

 Smoker n (%)—Ex

 Never

 Current

1 (14)

6 (86)

0 (0)

4 (27)

10 (67)

1 (6)

0.744

 Hypertension n (%)

6 (86)

14 (93)

1.0

 Hypercholesterolaemia n (%)

4 (57)

11 (73)

0.630

 Peritoneal dialysis n (%)

5 (71)

9 (60)

1.0

 Duration of dialysis (months)

5 (4–48)

6 (4–9)

0.797

 ACE inhibitor n (%)

1 (14)

4 (27)

1.0

 ARB n (%)

1 (14)

3 (20)

1.0

 Statin n (%)

1 (14)

8 (53)

0.165

 Loop diuretic n (%)

5 (71)

5 (33)

0.172

 Calcium channel blocker n (%)

5 (71)

9 (60)

1.0

 Beta blocker n (%)

2 (29)

3 (20)

1.0

 Alpha blocker

3 (43)

4 (27)

0.630

 Erythropoietin treatment n (%)

5 (71)

4 (27)

0.074

Laboratory data

 Haemoglobin (g/L)

102 ± 12

117 ± 11

0.008

 Haematocrit (%)

31.2 ± 3.3

35.4 ± 3.7

0.019

 Mean cell volume (fl.)

88.9 ± 3.3

91.6 ± 3.7

0.118

 Urea (mmol/L)

21.8 ± 6.2

22.1 ± 5.6

0.902

 Creatinine (µmol/L)

673 ± 300

606 ± 192

0.534

 ACR (mg/mmol)

204 (109.3-277.8)

77.4 (62.8-199.4)

0.239

 Iron (µmol/L)

11.8 (9.5–13)

12.9 (9.4–16)

0.494

 Transferrin (g/L)

1.92 ± 0.54

2.06 ± 0.4

0.525

 Albumin (g/L)

35 ± 6

40 ± 7

0.125

 Corrected calcium (mmol/L)

2.45 ± 0.13

2.33 ± 0.17

0.123

 hsCRP (mg/L)

1.9 (1-3.6)

2.8 (1.9-8)

0.312

 NT pro-BNP (ng/L)

1900 (522–4597)

441 (342–643)

0.416

 Phosphate (mmol/L)

1.71 (1.55–2.07)

1.59 (1.53–1.69)

0.312

 PTH (µmol/L)

41.7 ± 23.2

30.5 ± 16.9

0.271

 Total cholesterol (mmol/L)

4.8 ± 1.7

5.0 ± 1.4

0.772

Haemodynamic data

 Systolic BP (mmHg)

129 ± 25

137 ± 20

0.398

 Diastolic BP (mmHg)

83 ± 14

85 ± 8

0.798

 Heart Rate (bpm)

72 ± 14

66 ± 8

0.156

  1. Data are presented as mean ± SD or median (IQR). Variables highlighted in bold demonstrated a significant difference between the two groups
  2. CFVR, coronary flow velocity reserve; BMI, body mass index; ACE, angiotensin converting enzyme; ARB, angiotensin receptor blocker; ACR, albumin creatinine ratio; hsCRP, high sensitivity C reactive peptide; NT-proBNP, N terminal pro brain natriuretic peptide; PTH, parathyroid hormone; BP, blood pressure; bpm, beats per minute