Fig. 5

Results of primary outcomes of EMPA group: a comparison between early and advanced DMCMP groups. Left ventricular global longitudinal strain (LVGLS; absolute value) and the ratio of early diastolic mitral inflow velocity to early diastolic mitral annular velocity (E/e′) at baseline and 12 months after administration of empagliflozin are shown in (a) and (c). The primary outcomes, changes in LVGLS and E/e′ between 12 months (ΔLVGLS and ΔE/e′) are shown in (b) and (d). Improvements in LVGLS and E/eʹ are more remarkable in the early DMCMP group than in the advanced DMCMP group