Baseline characteristics | NT-proBNP (Q1 < 96 pg/ml) N = 257 | NT-proBNP (96 pg/ml < Q2 < 328 pg/ml) N = 255 | NT-proBNP (328 pg/ml < Q3 < 1287 pg/ml) N = 255 | NT-proBNP (Q4 > 1287 pg/ml) N = 255 | P value |
---|---|---|---|---|---|
General characteristics | |||||
Mean age (SD), y | 61.02 ± 10.11 | 65.05 ± 10.25 | 66.94 ± 10.45 | 70.09 ± 8.90 |  < 0.001 |
Age ≥ 65y, No. (%) | 103 (40.1) | 134 (52.5) | 158 (62.0) | 190 (74.5) |  < 0.001 |
Female, No. (%) | 61 (23.7) | 53 (20.8) | 72 (28.2) | 76 (29.8) | 0.076 |
Weight, mean (SD), kg | 68.29 ± 11.59 | 67.47 ± 12.29 | 65.91 ± 13.49 | 62.28 ± 13.89 |  < 0.001 |
Heart rate, mean (SD), bpm | 74.38 ± 10.27 | 72.79 ± 10.77 | 75.15 ± 12.69 | 80.66 ± 16.02 |  < 0.001 |
LVEF, mean (SD), % | 67.60 ± 5.09 | 65.21 ± 7.55 | 59.59 ± 11.10 | 49.85 ± 14.66 |  < 0.001 |
Anaemia, No. (%) | 49 (19.1) | 65 (25.5) | 98 (38.4) | 148 (58.0) |  < 0.001 |
Serum creatinine level, mean (SD), μmol/dL | 0.93 ± 0.25 | 0.99 ± 0.26 | 1.10 ± 0.48 | 1.60 ± 1.60 |  < 0.001 |
Disease type, No. (%) | |||||
NSTEMI | 44 (17.1) | 64 (25.3) | 83 (32.5) | 126 (49.4) |  < 0.001 |
Unstable angina | 213 (82.9) | 189 (74.7) | 172 (67.5) | 129 (50.6) | NA |
eGFR, mL/min/1.73m2 | |||||
Mean (SD), | 88.77 ± 23.41 | 82.22 ± 23.63 | 76.04 ± 27.49 | 59.53 ± 25.68 |  < 0.001 |
 ≤ 60 mL/min/1.73m2, No. (%) | 27 (10.5) | 42 (16.5) | 68 (26.7) | 133 (52.2) |  < 0.001 |
Risk factors and prior medical history, No. (%) | |||||
Current smoker | 74 (28.8) | 71 (27.8) | 80 (31.4) | 69 (27.1) | 0.726 |
Hypertension | 169 (65.8) | 183 (71.8) | 171 (67.1) | 183 (71.8) | 0.316 |
Diabetes | 89 (34.6) | 80 (31.4) | 92 (36.1) | 120 (47.1) | 0.002 |
Cardiac arrest | 0 (0.0) | 0 (0.0) | 1 (0.4) | 1 (0.4) | 0.570 |
Chronic heart failure | 18 (7.0) | 21 (8.2) | 46 (18.0) | 107 (42.0) |  < 0.001 |
Myocardial infarction | 23 (8.9) | 28 (11.0) | 67 (26.3) | 74 (29.0) |  < 0.001 |
Percutaneous coronary intervention | 64 (24.9) | 42 (16.5) | 35 (13.7) | 49 (19.2) | 0.009 |
Coronary artery bypass surgery | 2 (0.8) | 3 (1.2) | 2 (0.8) | 4 (1.6) | 0.796 |
Stroke | 8 (3.1) | 23 (9.0) | 32 (12.5) | 35 (13.7) |  < 0.001 |
Treated lesion, No. (%) | |||||
LM | 25 (9.7) | 31 (12.2) | 35 (13.8) | 36 (14.2) | 0.402 |
LAD | 161 (62.6) | 170 (66.9) | 168 (66.4) | 163 (64.4) | 0.730 |
LCX | 92 (35.8) | 117 (46.1) | 121 (47.8) | 99 (39.1) | 0.017 |
RCA | 120 (46.7) | 120 (47.2) | 102 (40.3) | 101 (39.9) | 0.181 |
Multivessel intervention | 122 (47.5) | 139 (54.7) | 132 (52.2) | 109 (43.1) | 0.044 |
Completeness of revascularization | 59 (23.0) | 69 (27.2) | 55 (21.7) | 33 (13.0) | 0.001 |
Drug eluting stent type, No. (%) | |||||
First generation | 122 (53.0) | 131 (60.4) | 132 (62.6) | 144 (74.6) |  < 0.001 |
Second generation | 108 (47.0) | 86 (39.6) | 79 (37.4) | 49 (25.4) | NA |