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Table 4 Effect of irbesartan on the expression of CD163, CD206, IL-10 and TNF-α in LVH patients

From: Effects of irbesartan on phenotypic alterations in monocytes and the inflammatory status of hypertensive patients with left ventricular hypertrophy

 

Control

Irbesartan

F

P

10−6 mol/L

10−7 mol/L

10−8 mol/L

CD163 (%)

68.69 ± 14.90

80.76 ± 18.61*

76.19 ± 10.25ab

72.45 ± 8.27abc

10.74

< 0.001

CD206 (%)

12.42 ± 7.58

16.61 ± 8.69*

15.76 ± 6.83ab

13.94 ± 5.17abc

12.90

0.028

IL-10 (ng/mL)

3.32 ± 0.90

5.42 ± 0.77*

4.51 ± 0.43ab

3.64 ± 0.49abc

11.63

< 0.001

TNF-α (pg/mL)

35.69 ± 4.79

25.93 ± 4.44*

27.37 ± 3.19ab

30.04 ± 6.21abc

4.81

0.011

  1. *P < 0.01 versus control
  2. aP < 0.05 versus control
  3. bP < 0.05 versus 10−6 mol/L group
  4. cP < 0.05 versus 10−7 mol/L group