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Table 1 Baseline characteristics

From: Hemodynamic change in patients with hypertrophic obstructive cardiomyopathy before and after alcohol septal ablation using 4D flow magnetic resonance imaging: a retrospective observational study

Number of patients

n = 11

Age, years

67.2 ± 12.2

Male, n (%)

3 (27.3)

BMI, kg/m2

22.4 ± 2.5

NYHA class III or IV, n (%)

7 (63.6)

Syncope, n (%)

1 (9.1)

Hypertension, n (%)

4 (36.4)

Diabetes mellitus, n (%)

0 (0.0)

Dyslipidemia, n (%)

4 (36.4)

COPD, n (%)

0 (0.0)

Current smoking, n (%)

0 (0.0)

CPA, n (%)

0 (0.0)

Stroke, n (%)

0 (0.0)

Atrial fibrillation, n (%)

2 (18.2)

CIED implantation, n (%)

0 (0.0)

Family history of SCD, n (%)

1 (9.1)

Family history of HCM, n (%)

3 (27.3)

Medication

 

 Na channel blockers, n (%)

8 (72.7)

 Beta blockers, n (%)

10 (90.9)

 Calcium channel antagonists, n (%)

7 (63.6)

 ACE-Is/ARBs, n (%)

1 (9.1)

 Amiodarones, n (%)

1 (9.1)

 OACs, n (%)

2 (18.2)

Laboratory data

 

 NT-proBNP, pg/mL

1610.5 (211.0–5060.0)

Echocardiographic variables

 

 LVEDD, mm

41.4 ± 4.0

 LVESD, mm

24.6 ± 3.8

 Max-IVST, mm

17.6 ± 4.4

 LAD, mm

40.5 ± 5.1

 LAVI, mL/m2

58.8 ± 16.9

 Resting LVOT PPG, mmHg

108.7 ± 68.8

 Moderate or severe MR, n (%)

7 (63.6)

 Anterior leaflet length of MV, mm

25.9 ± 4.7

 Posterior leaflet length of MV, mm

17.4 ± 4.0

 SAM grade of MV

 

 G0, n (%)

1 (9.1)

 G1, n (%)

0 (0.0)

 G2, n (%)

1 (9.1)

 G3, n (%)

5 (45.4)

 G4, n (%)

4 (36.3)

  1. Data are expressed as mean ± standard deviation or median (interquartile range) and number (%)
  2. ACE-Is, angiotensin-converting enzyme inhibitors; ARBs, angiotensin receptor blockers; BMI, body mass index; CIED, cardiac implantable electrical device; COPD, chronic obstructive pulmonary disease; CPA, cardiopulmonary arrest; G0–4, grade 0–4; HCM, hypertrophic cardiomyopathy; LAD, left atrial dimension; LAVI, left atrial volume index; LVEDD, left ventricular end-diastolic dimension; LVESD, left ventricular end-systolic dimension; LVOT PPG, peak pressure gradient at left ventricular outflow tract; Max-IVST, maximum interventricular septal thickness; MR, mitral regurgitation; MV, mitral valve; NT-proBNP, N-terminal prohormone of B-type natriuretic peptide; NYHA, New York Heart Association; OACs, oral anticoagulants; SAM, systolic anterior motion; SCD, sudden cardiac death