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Table 5 Determinants of global longitudinal early diastolic strain rate

From: Characterization of subclinical diastolic dysfunction by cardiac magnetic resonance feature-tracking in adult survivors of non-Hodgkin lymphoma treated with anthracyclines

Independent variables

Dependent variable (GLSR-E)

Univariate analysis

Multiple Analysis (r2 0.44, p < 0.001)

B Coef

95% CI

p

B Coef

95% CI

p

Cumulative dose

− 0.03

(− 0.06;− 0.01)

0.009

Time after therapy

0.07

(− 0.05;0.19)

0.245

Age (years)

− 0.28

(− 0.70;0.13)

0.173

− 0.43

(− 0.76;0.10)

0.012

Gender (female)

7.45

(− 4.70;19.60)

0.212

Smoking (Yes)

− 0.56

(− 36.63;35.51)

0.975

Hypertension (no)

9.12

(− 4.24;22.48)

0.174

Diabetes (no)

− 13.74

(− 34.65;7.16)

0.190

Dyslipidemia (no)

12.87

(− 22.91;48.65)

0.469

Prior radiotherapy (no)

− 2.80

(− 28.67;23.07)

0.827

LVEF

1.25

(0.47;2.02)

0.002

LVMi

− 0.25

(− 0.85;0.33)

0.384

LGE (no)

− 2.80

(− 28.67;23.07)

0.827

Native T1

− 0.05

(− 0.23;0.13)

0.559

ECV

0.33

(− 1.64;2.31)

0.730

T2

− 0.27

(− 3.41;2.87)

0.861

GLS

− 3.65

(− 5.53;− 1.77)

 < 0.001

− 4.09

(− 5.86;− 2.33)

 < 0.001

  1. LVEF left ventricular ejection fraction, LVMi left ventricular mass index, LGE late gadolinium enhancement, ECV extracellular volume fraction, GLS global longitudinal strain