| 0 ppm | 20 ppm | Total | p |
---|---|---|---|---|
BSA m2 | 1.2 ± 0.1 | 1.3 ± 0.1 | 1.3 ± 0.1 | 0.271 |
Baseline | ||||
HR min−1 | 85.6 ± 13.9 | 98.4 ± 11.6 | 92.0 ± 13.8 | 0.152 |
SBP mmHg | 129.2 ± 16.5 | 126.4 ± 20.3 | 127.8 ± 17.5 | 0.817 |
DBP mmHg | 68.6 ± 8.6 | 67.4 ± 5.9 | 68.0 ± 7.0 | 0.805 |
SPAP mmHg | 26.6 ± 2.8 | 24.8 ± 3.6 | 25.7 ± 3.2 | 0.400 |
DPAP mmHg | 14.2 ± 2.7 | 12.4 ± 2.9 | 13.3 ± 2.8 | 0.337 |
COPWD L/min | 6.9 ± 1.7 | 7.0 ± 0.8 | 7.0 ± 1.3 | 0.878 |
COTD L/min | 6.7 ± 1.5 | 7.3 ± 0.7 | 7.0 ± 1.2 | 0.459 |
Cardiac arrest | ||||
COPWD L/min | 1.7 ± 0.2 | 1.8 ± 0.2 | 1.8 ± 0.2 | 0.341 |
Impella flow L/min | 1.9 ± 0.3 | 1.9 ± 0.2 | 1.9 ± 0.2 | 0.892 |
HRpp-VF min−1 | 20.8 ± 1.1 | 21.4 ± 0.8 | 21.1 ± 0.9 | 0.491 |
30Â min post-ROSC | ||||
HR min−1 | 115 ± 24.3 | 130 ± 30 | 128 ± 36 | 0.055 |
SBP mmHg | 95.2 ± 12.9 | 95.6 ± 25.1 | 95.4 ± 18.8 | 0.976 |
DBP mmHg | 64.8 ± 10.6 | 64.4 ± 10.9 | 64.6 ± 10.1 | 0.955 |
SPAP mmHg | 26.2 ± 3.8 | 25.2 ± 6.2 | 25.7 ± 4.9 | 0.766 |
DPAP mmHg | 14.4 ± 3.5 | 11.8 ± 5.3 | 13.1 ± 4.5 | 0.388 |
COTD L/min | 5.5 ± 1.7 | 5.6 ± 1.2 | 5.6 ± 1.4 | 0.900 |
COPWD L/min | 5.1 ± 1.1 | 5.7 ± 1.2 | 5.4 ± 1.1 | 0.433 |
3Â h post-ROSC | ||||
HR min−1 | 102.8 ± 13.9 | 111.6 ± 21.6 | 107.2 ± 17.7 | 0.466 |
SBP mmHg | 99.6 ± 8.6 | 114.2 ± 28.0 | 106.9 ± 21.0 | 0.298 |
DBP mmHg | 68.0 ± 7.3 | 65.0 ± 11.7 | 66.5 ± 9.3 | 0.639 |
SPAP mmHg | 28.0 ± 5.5 | 28.4 ± 4.6 | 28.2 ± 4.8 | 0.903 |
DPAP mmHg | 15.0 ± 3.2 | 14.4 ± 3.6 | 14.7 ± 3.3 | 0.790 |
COPWD L/min_ | 4.6 ± 1.0 | 6.6 ± 1.1 | 5.7 ± 1.5 | 0.016 |
COTD L/min | 5.1 ± 0.8 | 6.8 ± 2.3 | 5.9 ± 1.8 | 0.172 |
5Â h post-ROSC | ||||
HR min−1 | 75.0 ± 11.0 | 104.8 ± 19.6 | 89.9 ± 21.7 | 0.018 |
SBP mmHg | 110.2 ± 13.8 | 113.0 ± 18.0 | 111.6 ± 15.2 | 0.790 |
DBP mmHg | 68.0 ± 9.8 | 66.2 ± 9.0 | 67.1 ± 8.9 | 0.771 |
SPAP mmHg | 32.0 ± 4.4 | 23.0 ± 1.0 | 27.5 ± 5.6 | 0.008 |
DPAP mmHg | 16.2 ± 3.7 | 11.8 ± 1.3 | 14.0 ± 3.5 | 0.037 |
COPWD L/min_ | 4.0 ± 0.6 | 5.8 ± 1.0 | 4.9 ± 1.2 | 0.036 |
COTD L/min | 3.5 ± 0.6 | 5.6 ± 1.5 | 4.5 ± 1.6 | 0.021 |