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Table 2 Significant independent predictors of early postoperative AF development on multivariate analysis

From: Biochemical predictors of postoperative atrial fibrillation following cardiac surgery

Predictors

Predictors for any AF*

Predictors for persistent AF*

Clinical/surgical predictors

Low EF (< 60%)

2.6, 95% CI 2.0–3.4, p < 0.001

1.9, 95% CI 1.2–2.9, p = 0.008

Valvular intervention

2.4, 95% CI 1.8–3.2, p < 0.001

2.4, 95% CI 1.6–3.8, p < 0.001

Diabetes

1.6, 95% CI 1.2–2.2, p = 0.004

2.1, 95% CI 1.3–3.3, p = 0.002

COPD

 

1.8, 95% CI 1.1–2.9, p = 0.018

Previous cardiac surgery

 

3.1, 95% CI 1.7–5.8, p < 0.001

Hematological/biochemical predictors

Low hematocrit (< 35%)

2.1, 95% CI 1.5–2.9, p < 0.001

1.9, 95% CI 1.2–2.9, p = 0.006

Low thrombocyte (< 142 × 109/L)

5.6, 95% CI 1.1–29.3, p = 0.042

 

Low LDL (< 100 mg/dL)

1.6, 95% CI 1.2–2.1, p = 0.004

2.1, 95% CI 1.3–3.1, p = 0.001

High direct bilirubin (> 0.5 mg/dL)

2.0, 95% CI 1.4–2.9, p < 0.001

 

Low GFR (≤ 90 mL/min/1.73m2)

1.6, 95% CI 1.1–2.4, p = 0.026

 

High CRP (> 5 mg/L)

2.0, 95% CI 1.2–3.2, p = 0.004

2.7, 95% CI 1.5–4.7, p = 0.001

High HbA1c (> 6.5%)

 

2.0, 95% CI 1.3–3.1, p = 0.001

  1. AF, atrial fibrillation; COPD, chronic obstructive pulmonary disease; CRP, C-reactive protein; EF, ejection fraction; GFR, glomerular filtration rate; LDL, low-density lipoprotein
  2. *Odds ratio, 95% confidence interval, p value