| |
Tertile 1 (n = 404)
|
Tertile 2 (n = 406)
|
Tertile 3 (n = 405)
|
p value
|
|---|
|
Male, n(%)
|
273 (67.5%)
|
282 (69.4%)
|
273 (67.4%)
|
0.785
|
|
Age, years
|
66.2 ± 12.5
|
65.7 ± 11.8
|
65.9 ± 12.1
|
0.729
|
|
BMI, kg/m2
|
26.2 ± 3.7
|
26.9 ± 3.6
|
25.2 ± 3.6
|
0.002
|
|
STEMI, n(%)
|
160 (39.6%)
|
197 (48.5%)
|
227 (56.0%)
|
< 0.001
|
|
Cardiovascular risk factors
|
|
Hypertension
|
291 (72.0%)
|
268 (66.0%)
|
288 (71.1%)
|
0.167
|
|
Dyslipidemia
|
197 (48.37%)
|
181 (44.5%)
|
181 (44.6%)
|
0.397
|
|
Previous MI
|
48 (11.8%)
|
46 (11.3%)
|
33 (8.1%)
|
0.173
|
|
Prior PCI
|
69 (17.0%)
|
70 (17.2%)
|
60 (14.8%)
|
0.580
|
|
CKD
|
49 (12.1%)
|
45 (11.0%)
|
63 (15.5%)
|
0.139
|
|
Smoking
|
235 (58.1%)
|
248 (61.0%)
|
224 (55.3%)
|
0.249
|
|
LVEF (%)
|
57.3 ± 10.8
|
56.4 ± 11.2
|
55.6 ± 11.3
|
0.114
|
|
Laboratory assessment
|
|
ABG, mmol/L
|
8.25 ± 2.59
|
11.23 ± 3.32
|
15.18 ± 4.97
|
< 0.001
|
|
HbA1c, %
|
7.66 ± 1.72
|
7.58 ± 1.69
|
7.40 ± 1.55
|
< 0.001
|
|
Hemoglobin, g/L
|
126.9 ± 24.5
|
131.1 ± 23.7
|
129.6 ± 22.7
|
0.025
|
|
Albumin, g/dL
|
35.8 ± 4.8
|
34.9 ± 7.7
|
35.4 ± 5.9
|
0.921
|
|
eGFR, ml/(min*1.73m2)
|
74.6 ± 23.9
|
75.8 ± 24.0
|
72.1 ± 26.5
|
0.180
|
|
NT-proBNP, pg/mL
|
1653 (551, 5926)
|
1874 (653, 6114)
|
2302 (713, 7778)
|
0.036
|
|
Peak TnI, ng/mL
|
2.6 (0.5, 11.4)
|
5.7 (1.5, 22.2)
|
6.9 (1.6, 24.4)
|
< 0.001
|
|
hs-CRP, mg/L
|
6.8 (2.2, 14.8)
|
7.5 (1.9, 17.6)
|
7.7 (2.3, 20.6)
|
0.256
|
|
In-hospital medication
|
|
Anti-platelet agents
|
387 (95.7%)
|
394 (97.0%)
|
389 (96.0%)
|
0.525
|
|
Statin
|
365 (90.3%)
|
364 (89.6%)
|
358 (88.3%)
|
0.657
|
|
ACEI or ARB
|
335 (82.9%)
|
342 (84.2%)
|
330 (81.4%)
|
0.436
|
|
Beta-blocker
|
323 (79.9%)
|
313 (77.0%)
|
311 (76.7%)
|
0.239
|
|
Diuretics
|
72 (17.8%)
|
64 (15.7%)
|
68 (16.7%)
|
0.665
|
|
PCI, n(%)
|
282 (69.8%)
|
304 (74.8%)
|
293 (72.3%)
|
0.272
|
|
IABP, n(%)
|
7 (1.7%)
|
13 (3.2%)
|
14 (3.4%)
|
0.276
|
|
In-hospital outcomes
|
|
AKI
|
18 (4.4%)
|
32 (7.8%)
|
53 (13.0%)
|
< 0.001
|
|
All-cause death
|
11 (2.7%)
|
15 (3.6%)
|
26 (6.4%)
|
0.027
|
|
Cardiogenic shock
|
20 (4.9%)
|
31 (7.6%)
|
47 (11.6%)
|
0.002
|
- Diabetic patients with AMI were divided according to the tertile levels of SHR (Tertile 1: SHR < 1.04; Tertile 2:1.04 ≤ SHR < 1.33; Tertile 3: SHR ≥ 1.33)
- BMI: body mass index, STEMI: ST-segment elevation myocardial infarction, CKD: chronic kidney disease, PCI: percutaneous coronary intervention, LVEF: left ventricular ejection fraction, SHR: stress hyperglycemia ratio, ABG: admission blood glucose, HbA1c: glycated hemoglobin, eGFR: estimated glomerular filtration rate, NT-proBNP: N-terminal B-type natriuretic peptide, TnI: Troponin I, AKI: acute kidney injury
