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Table 1 Characteristics of patients in the training and validation cohorts

From: Distinguishing cardiac myxomas from cardiac thrombi by a radiomics signature based on cardiovascular contrast-enhanced computed tomography images

  The primary group p The validation group p
Myxoma (41) Thrombus (35) Myxoma (18) Thrombus (15)
Sex    0.684    0.373
 Female 23 (56.1) 17 (48.6)   10 (55.6) 6 (40.0)  
 Male 18 (43.9) 18 (51.4)   8 (44.4) 9 (60.0)  
Age(years) 60.98 ± 12.62 56.38 ± 15.35 0.054 62.94 ± 12.92 62.27 ± 12.20 0.873
Clinical manifestation    0.146    0.061
 Cardiac signs 27 (55.1) 30 (73.2)   9 (45.0) 13 (86.7)  
 Embolism 12 (24.5) 9 (22.0)   6 (30.0) 2 (13.3)  
 Constitutional symptoms 3 (6.1) 1 (2.4)   2 (10.0) 0 (0.0)  
 No symptom 7 (14.3) 1 (2.4)   3 (15.0) 0 (0.0)  
Medical records    0.011*    0.010*
 Diabetes mellitus 3 (6.7) 3 (3.1)   4 (26.7) 4 (10.5)  
 Hypertension 9 (20.0) 7 (7.1)   5 (33.3) 5 (13.2)  
 Atrial fibrillation 4 (8.9) 15 (15.3)   0 (0.0) 12 (31.6)  
 Rheumatic heart disease 2 (4.4) 28 (28.6)   0 (0.0) 5 (13.2)  
 Heart valves obstruction 8 (17.8) 14 (14.3)   1 (6.7) 3 (7.9)  
 Heart valves insufficiency 12 (26.7) 19 (19.4)   5 (33.3) 5 (13.2)  
 Others 7 (15.6) 12 (12.2)   0 (0.0) 4 (10.5)  
 Heart rate 82.00 ± 9.26 89.51 ± 21.65 0.076 82.17 ± 12.61 87.40 ± 13.34 0.244
 Cardiac murmur 19 (46.3) 14 (40.0) 0.373 4 (26.7) 7 (46.7) 0.133
Naked eye findings       
 Calcification 8 (19.5) 4 (11.4) 0.367 2 (11.1) 3 (20.0) 0.639
 Hydrothorax 4 (9.8) 9 (25.7) 0.066 1 (5.6) 6 (40.0) 0.030*
 Pericardial effusion 9 (22.0) 13 (37.1) 0.146 2 (11.1) 8 (53.3) 0.020*
 Heart enlargement 25 (61.0) 29 (85.3) 0.036* 8 (44.4) 12 (80.0) 0.037*
 Homogeneous density 27 (65.9) 26 (74.3) 0.425 12 (66.7) 11 (73.3) 0.722
 Surface    0.041*    0.048*
  Coarse 24 (58.5) 12 (34.3)   11 (61.1) 4 (26.7)  
  Smooth 17 (41.5) 23 (65.7)   7 (38.9) 11 (73.3)  
 Location    0.498    0.375
  LA 37 (90.2) 29 (82.9)   16 (88.9) 11 (73.3)  
  RA 4 (9.8) 6 (17.1)   2 (11.1) 4 (26.7)  
  1. *p value < 0.05; ages and heart rate are shown as mean ± standard deviation; other data are the number of patients with the percentage in Parentheses
  2. Cardiac signs included: Dyspnea, palpitations, malaise or syncope, chest pain or discomfort, dizziness, lower limb edema and hemoptysis
  3. Constitutional symptoms included: fever, weight loss, anemia, or pseudo-connective tissue disease signs
  4. Others included: Patent foramen ovale, Pulmonary hypertension, cardiomyopathy and arrhythmia. LA: left atrium, RA: right atrium