Fig. 3

Changes in the heart function of rats from each group. a Changes of the MAP in rats in each group. b Changes in the HR in-vivo rats in each group. T0, 5 min before CPB; T1, at the beginning of CPB; T2, at cardiac arrest; T3, at the end of cardiac arrest; T4, after 5 min of reperfusion; T5, at the end of reperfusion. ^aP < 0.05 versus T0; ^bP < 0.05 versus. T4 in the N group; ^cP < 0.05 versus T5 in the N group. MAP mean arterial pressure, DM diabetes mellitus, HR heart rate, N normal, IR ischemia–reperfusion, IPO ischemia post-conditioning, DM + IPO DM ischemia post-conditioning; DM + IPO + dme DM ischemia post-conditioning with inhibitor