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Table 5 Logistic regression analysis of in-hospital mortality

From: Insight into the epidemiology of infective endocarditis in Portugal: a contemporary nationwide study from 2010 to 2018

 

Bivariate analysis

Full model

Stepwise model

OR

95% CI

p

Adjusted OR

95% CI

p

Adjusted OR

95% CI

p

Age group, years old

 70–79

0.906

0.797

1.030

0.131

0.793

0.685

0.918

0.002

0.806

0.697

0.931

0.003

 60–69

0.683

0.570

0.815

< 0.001

0.519

0.418

0.644

< 0.001

0.528

0.427

0.652

< 0.001

 40–59

0.257

0.178

0.361

< 0.001

0.182

0.119

0.272

< 0.001

0.186

0.122

0.276

< 0.001

 18–39

0.114

0.028

0.304

< 0.001

0.117

0.028

0.327

< 0.001

0.117

0.028

0.327

< 0.001

 Length of stay (days)

0.998

0.996

1.000

0.037

0.989

0.986

0.992

< 0.001

0.990

0.987

0.992

< 0.001

Previous medical history

 Cardiac valve disease

1.192

1.041

1.363

0.010

1.234

1.052

1.446

0.010

1.234

1.051

1.445

0.010

 Rheumatic valve disease

1.241

1.030

1.489

0.021

1.188

0.962

1.460

0.106

1.186

0.961

1.456

0.107

 Cardiac devices

1.135

0.931

1.375

0.5

0.994

0.798

1.231

0.957

    

 Arterial hypertension

0.740

0.656

0.834

< 0.001

0.703

0.612

0.807

< 0.001

0.705

0.614

0.808

< 0.001

 Atrial fibrillation

1.200

1.056

1.362

0.005

0.929

0.803

1.073

0.318

    

 Diabetes mellitus

1.275

1.126

1.442

< 0.001

1.056

0.916

1.215

0.453

    

 HIV

1.618

1.094

2.346

0.013

2.548

1.614

3.958

< 0.001

2.554

1.619

3.961

< 0.001

 Chronic renal failure

1.685

1.436

1.973

< 0.001

1.230

0.995

1.515

0.054

1.298

1.081

1.555

0.005

 Chronic renal failure on hemodialysis

1.679

1.307

2.142

< 0.001

1.143

0.824

1.580

0.420

    

 Cancer

1.215

1.035

1.422

0.016

1.271

1.065

1.513

0.007

1.277

1.070

1.520

0.006

 Chronic hepatic disease

1.753

1.386

2.204

< 0.001

1.623

1.239

2.112

< 0.001

1.628

1.243

2.118

< 0.001

Infectious agents

 Staphylococcus

2.314

2.021

2.647

< 0.001

1.836

1.551

2.171

< 0.001

1.825

1.547

2.151

< 0.001

 Enterococcus

1.199

0.968

1.475

0.090

1.187

0.931

1.505

0.161

    

 Anaerobes

2.162

0.811

5.289

0.101

1.748

0.591

4.766

0.289

    

 Gram negative

1.487

1.264

1.744

< 0.001

1.215

1.008

1.460

0.039

1.220

1.012

1.465

0.035

In-hospital complications

 Acute myocardial infarct

2.361

1.777

3.117

< 0.001

1.899

1.382

2.591

< 0.001

1.908

1.388

2.604

< 0.001

 Heart failure

1.503

1.335

1.693

< 0.001

1.445

1.260

1.657

< 0.001

1.424

1.245

1.629

< 0.001

 Ischemic stroke

2.198

1.857

2.597

< 0.001

2.265

1.871

2.737

< 0.001

2.259

1.868

2.726

< 0.001

 Transient ischemic accident

0.111

0.006

0.512

0.030

0.118

0.007

0.562

0.037

0.121

0.007

0.577

0.039

 Hemorrhagic stroke

3.299

2.483

4.371

< 0.001

3.933

2.848

5.414

< 0.001

3.893

2.823

5.354

< 0.001

 Acute renal failure

3.378

2.899

3.933

< 0.001

2.651

2.221

3.162

< 0.001

2.641

2.214

3.146

< 0.001

 Systemic embolism

1.810

1.157

2.766

0.007

1.014

0.590

1.703

0.960

    

 Central nervous system abscess/meningitis

1.442

0.884

2.273

0.127

0.982

0.556

1.687

0.948

    

 Sepsis

5.868

5.088

6.769

< 0.001

4.673

3.969

5.505

< 0.001

4.724

4.016

5.560

< 0.001

 Cardiac surgery

0.712

0.589

0.855

< 0.001

0.689

0.547

0.864

0.001

0.692

0.550

0.867

0.001

  1. Age group reference: 80 +; for medical history conditions, infectious agents, in-hospital complications, and cardiac surgery reference categories were: “Absence/No”
  2. CI confidence interval, HIV human immunodeficiency virus, OR odds ratio
  3. Values in Italic highlight p values < 0.05