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Table 1 Baseline characteristics of the study population

From: Prognostic dynamic nomogram integrated with metabolic acidosis for in-hospital mortality and organ malperfusion in acute type B aortic dissection patients undergoing thoracic endovascular aortic repair

Variables Derivation cohort (n = 286) External validation cohort (n = 77) P
Age, years 53 ± 11 55 ± 12 0.276
Male 255 (89.2) 71 (92.2) 0.433
Comorbidities
 Hypertension 246 (86.0) 64 (83.1) 0.523
 Diabetes mellitus 15 (5.2) 6 (7.8) 0.411
 Coronary artery disease 37 (12.9) 14 (18.2) 0.240
 Dyslipidemia/statin use 33 (11.5) 11 (14.3) 0.512
 Renal dysfunction 54 (18.9) 15 (19.5) 0.905
 Stroke 11 (3.8) 6 (7.8) 0.218
Anemia 140 (49.0) 35 (45.5) 0.586
 Organ malperfusion
  Extremity 31 (10.8) 10 (13.0) 0.597
  Abdominal organs 175 (61.2) 45 (58.4) 0.661
Laboratory findings
 Base excess value − 2.6 (− 5.7 to − 0.1) − 2.0 (− 4.9 to 0.3) 0.257
 Base excess stratification    0.682
  ≥ 0 68 (23.8) 20 (26.0)  
  − 5 to 0 138 (48.3) 41 (53.2)  
  − 10 to − 5 61 (21.3) 12 (15.6)  
  ≤ − 10 19 (6.6) 4 (5.2)  
  pH 7.40 (7.36–7.44) 7.40 (7.36–7.43) 0.623
 Bicarbonate, mmol/L 23.1 (21.0–24.5) 23.3 (21.6–25.2) 0.470
 Lactate 1.3 (0.8–2.3) 1.3 (0.9–2.2) 0.344
 Total cholesterol, mmol/L 4.4 ± 0.9 4.3 ± 1.1 0.311
 Triglyceride, mmol/L 1.4 (1.0–1.9) 1.3 (1.0–1.9) 0.659
 LDL-c, mmol/L 2.6 (2.1–3.1) 2.8 (1.9–3.2) 0.754
 Albumin ≤ 30 g/L 101 (35.3) 19 (24.7) 0.078
 D-dimer ≥ 5.44 μg/mL 63 (22.0) 24 (31.2) 0.095
 eGFR, mL·min−1·1.73 m−2 77.1 (46.3–96.9) 56.1 (42.5–79.9) 0.002
Imaging findings
 Diameter ≥ 55 mm 22 (7.7) 13 (16.9) 0.015
Extent of dissection    0.596
 Confined in thoracic aorta 52 (18.2%) 12 (15.6%)  
 Extended to abdominal aorta 234 (81.8%) 65 (84.4%)  
 False lumen patency    0.278
  Patent 200 (69.9) 60 (77.9)  
  Partially thrombosed 81 (28.3) 15 (19.5)  
  Completely thrombosed 5 (1.7) 2 (2.6)  
 Ejection fraction, % 64.5 (62.0–68.0) 65.0 (62.0–69.0) 0.956
 Blood supply of abdominal arteries
  Coeliac artery (TL/FL/TF) 185 (64.7)/92 (32.2)/9 (3.1) 47 (61.0)/25 (32.5)/5 (6.5) 0.372
  Superior mesenteric artery (TL/FL/TF) 217 (75.9)/57 (19.9)/12 (4.2) 60 (77.9)/12 (15.6)/5 (6.5) 0.499
  Left renal artery (TL/FL/TF) 196 (68.5)/81 (28.3)/9 (3.1) 52 (67.5)/22 (28.6)/3 (3.9) 0.908
  Right renal artery (TL/FL/TF) 209 (73.1)/68 (23.8)/9 (3.1) 54 (70.1)/18 (23.4)/5 (6.5) 0.397
  1. Data are presented as n (%) or mean ± standard deviation or median (quartiles 1 to 3); eGFR, estimated glomerular filtration rate; LDL-c, Low-density lipoprotein cholesterol; TL, true lumen; FL, false lumen; TF, true lumen and false lumen