Variables | Derivation cohort (n = 286) | External validation cohort (n = 77) | P |
---|---|---|---|
Age, years | 53 ± 11 | 55 ± 12 | 0.276 |
Male | 255 (89.2) | 71 (92.2) | 0.433 |
Comorbidities | |||
Hypertension | 246 (86.0) | 64 (83.1) | 0.523 |
Diabetes mellitus | 15 (5.2) | 6 (7.8) | 0.411 |
Coronary artery disease | 37 (12.9) | 14 (18.2) | 0.240 |
Dyslipidemia/statin use | 33 (11.5) | 11 (14.3) | 0.512 |
Renal dysfunction | 54 (18.9) | 15 (19.5) | 0.905 |
Stroke | 11 (3.8) | 6 (7.8) | 0.218 |
Anemia | 140 (49.0) | 35 (45.5) | 0.586 |
Organ malperfusion | |||
Extremity | 31 (10.8) | 10 (13.0) | 0.597 |
Abdominal organs | 175 (61.2) | 45 (58.4) | 0.661 |
Laboratory findings | |||
Base excess value | − 2.6 (− 5.7 to − 0.1) | − 2.0 (− 4.9 to 0.3) | 0.257 |
Base excess stratification | 0.682 | ||
≥ 0 | 68 (23.8) | 20 (26.0) | |
− 5 to 0 | 138 (48.3) | 41 (53.2) | |
− 10 to − 5 | 61 (21.3) | 12 (15.6) | |
≤ − 10 | 19 (6.6) | 4 (5.2) | |
pH | 7.40 (7.36–7.44) | 7.40 (7.36–7.43) | 0.623 |
Bicarbonate, mmol/L | 23.1 (21.0–24.5) | 23.3 (21.6–25.2) | 0.470 |
Lactate | 1.3 (0.8–2.3) | 1.3 (0.9–2.2) | 0.344 |
Total cholesterol, mmol/L | 4.4 ± 0.9 | 4.3 ± 1.1 | 0.311 |
Triglyceride, mmol/L | 1.4 (1.0–1.9) | 1.3 (1.0–1.9) | 0.659 |
LDL-c, mmol/L | 2.6 (2.1–3.1) | 2.8 (1.9–3.2) | 0.754 |
Albumin ≤ 30 g/L | 101 (35.3) | 19 (24.7) | 0.078 |
D-dimer ≥ 5.44 μg/mL | 63 (22.0) | 24 (31.2) | 0.095 |
eGFR, mL·min−1·1.73 m−2 | 77.1 (46.3–96.9) | 56.1 (42.5–79.9) | 0.002 |
Imaging findings | |||
Diameter ≥ 55 mm | 22 (7.7) | 13 (16.9) | 0.015 |
Extent of dissection | 0.596 | ||
Confined in thoracic aorta | 52 (18.2%) | 12 (15.6%) | |
Extended to abdominal aorta | 234 (81.8%) | 65 (84.4%) | |
False lumen patency | 0.278 | ||
Patent | 200 (69.9) | 60 (77.9) | |
Partially thrombosed | 81 (28.3) | 15 (19.5) | |
Completely thrombosed | 5 (1.7) | 2 (2.6) | |
Ejection fraction, % | 64.5 (62.0–68.0) | 65.0 (62.0–69.0) | 0.956 |
Blood supply of abdominal arteries | |||
Coeliac artery (TL/FL/TF) | 185 (64.7)/92 (32.2)/9 (3.1) | 47 (61.0)/25 (32.5)/5 (6.5) | 0.372 |
Superior mesenteric artery (TL/FL/TF) | 217 (75.9)/57 (19.9)/12 (4.2) | 60 (77.9)/12 (15.6)/5 (6.5) | 0.499 |
Left renal artery (TL/FL/TF) | 196 (68.5)/81 (28.3)/9 (3.1) | 52 (67.5)/22 (28.6)/3 (3.9) | 0.908 |
Right renal artery (TL/FL/TF) | 209 (73.1)/68 (23.8)/9 (3.1) | 54 (70.1)/18 (23.4)/5 (6.5) | 0.397 |