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Table 1 Baseline characteristics of the study population

From: Prognostic dynamic nomogram integrated with metabolic acidosis for in-hospital mortality and organ malperfusion in acute type B aortic dissection patients undergoing thoracic endovascular aortic repair

Variables

Derivation cohort (n = 286)

External validation cohort (n = 77)

P

Age, years

53 ± 11

55 ± 12

0.276

Male

255 (89.2)

71 (92.2)

0.433

Comorbidities

 Hypertension

246 (86.0)

64 (83.1)

0.523

 Diabetes mellitus

15 (5.2)

6 (7.8)

0.411

 Coronary artery disease

37 (12.9)

14 (18.2)

0.240

 Dyslipidemia/statin use

33 (11.5)

11 (14.3)

0.512

 Renal dysfunction

54 (18.9)

15 (19.5)

0.905

 Stroke

11 (3.8)

6 (7.8)

0.218

Anemia

140 (49.0)

35 (45.5)

0.586

 Organ malperfusion

  Extremity

31 (10.8)

10 (13.0)

0.597

  Abdominal organs

175 (61.2)

45 (58.4)

0.661

Laboratory findings

 Base excess value

− 2.6 (− 5.7 to − 0.1)

− 2.0 (− 4.9 to 0.3)

0.257

 Base excess stratification

  

0.682

  ≥ 0

68 (23.8)

20 (26.0)

 

  − 5 to 0

138 (48.3)

41 (53.2)

 

  − 10 to − 5

61 (21.3)

12 (15.6)

 

  ≤ − 10

19 (6.6)

4 (5.2)

 

  pH

7.40 (7.36–7.44)

7.40 (7.36–7.43)

0.623

 Bicarbonate, mmol/L

23.1 (21.0–24.5)

23.3 (21.6–25.2)

0.470

 Lactate

1.3 (0.8–2.3)

1.3 (0.9–2.2)

0.344

 Total cholesterol, mmol/L

4.4 ± 0.9

4.3 ± 1.1

0.311

 Triglyceride, mmol/L

1.4 (1.0–1.9)

1.3 (1.0–1.9)

0.659

 LDL-c, mmol/L

2.6 (2.1–3.1)

2.8 (1.9–3.2)

0.754

 Albumin ≤ 30 g/L

101 (35.3)

19 (24.7)

0.078

 D-dimer ≥ 5.44 μg/mL

63 (22.0)

24 (31.2)

0.095

 eGFR, mL·min−1·1.73 m−2

77.1 (46.3–96.9)

56.1 (42.5–79.9)

0.002

Imaging findings

 Diameter ≥ 55 mm

22 (7.7)

13 (16.9)

0.015

Extent of dissection

  

0.596

 Confined in thoracic aorta

52 (18.2%)

12 (15.6%)

 

 Extended to abdominal aorta

234 (81.8%)

65 (84.4%)

 

 False lumen patency

  

0.278

  Patent

200 (69.9)

60 (77.9)

 

  Partially thrombosed

81 (28.3)

15 (19.5)

 

  Completely thrombosed

5 (1.7)

2 (2.6)

 

 Ejection fraction, %

64.5 (62.0–68.0)

65.0 (62.0–69.0)

0.956

 Blood supply of abdominal arteries

  Coeliac artery (TL/FL/TF)

185 (64.7)/92 (32.2)/9 (3.1)

47 (61.0)/25 (32.5)/5 (6.5)

0.372

  Superior mesenteric artery (TL/FL/TF)

217 (75.9)/57 (19.9)/12 (4.2)

60 (77.9)/12 (15.6)/5 (6.5)

0.499

  Left renal artery (TL/FL/TF)

196 (68.5)/81 (28.3)/9 (3.1)

52 (67.5)/22 (28.6)/3 (3.9)

0.908

  Right renal artery (TL/FL/TF)

209 (73.1)/68 (23.8)/9 (3.1)

54 (70.1)/18 (23.4)/5 (6.5)

0.397

  1. Data are presented as n (%) or mean ± standard deviation or median (quartiles 1 to 3); eGFR, estimated glomerular filtration rate; LDL-c, Low-density lipoprotein cholesterol; TL, true lumen; FL, false lumen; TF, true lumen and false lumen