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Table 1 Baseline characteristics of the study cohort

From: Combined effect of menopause and cardiovascular risk factors on death and cardiovascular disease: a cohort study

 

All (n = 2104)

Menopause staging at baseline

Age at menopause

Reproductive (n = 1252)

Perimenopause (n = 309)

Early postmenopause (n = 283)

Late postmenopause (n = 260)

P value

< 45 years (n = 160)

45–49 years (n = 790)

50–51 years (n = 506)

52–53 years (n = 375)

≥ 54 years (n = 273)

P value

Age at baseline (years old), mean ± SD

45.2 ± 7.8

39.9 ± 3.5

48.9 ± 4.4

53.0 ± 3.9

57.6 ± 4.4

< 0.001

47.0 ± 8.1

43.6 ± 7.1

46.2 ± 8.1

45.2 ± 7.8

46.7 ± 7.9

< 0.001

Body mass index (kg/m2), mean ± SD

23.9 ± 3.4

23.9 ± 3.5

24.2 ± 3.3

23.8 ± 3.2

23.6 ± 3.1

0.29

24.4 ± 3.5

23.9 ± 3.5

23.5 ± 3.3

24.0 ± 3.2

24.0 ± 3.4

0.02

Smoking, n (%)

18 (0.9)

7 (0.6)

6 (1.9)

2 (0.7)

3 (1.2)

0.11

0 (0.0)

7 (0.9)

8 (1.6)

1 (0.3)

2 (0.7)

0.19

Systolic blood pressure (mmHg), mean ± SD

119.2 ± 18.1

114.5 ± 15.2

123.0 ± 17.9

125.2 ± 18.9

130.9 ± 22.1

< 0.001

121.9 ± 18.6

118.1 ± 17.7

119.3 ± 19.0

119.3 ± 17.8

120.3 ± 17.6

0.12

Diastolic blood pressure (mmHg), mean ± SD

75.6 ± 10.5

73.6 ± 9.7

77.9 ± 11.1

78.4 ± 10.8

79.9 ± 11.1

< 0.001

77.2 ± 10.7

75.1 ± 10.5

75.6 ± 10.7

75.5 ± 10.3

76.4 ± 10.5

0.11

Hypertension, n (%)

347 (16.5)

119 (9.5)

71 (23.1)

74 (26.1)

83 (31.9)

< 0.001

31 (19.4)

124 (15.7)

82 (16.2)

58 (15.5)

52 (19.0)

0.57

Total cholesterol (mmol/L), mean ± SD

4.67 ± 0.88

4.40 ± 0.77

4.84 ± 0.86

5.11 ± 0.82

5.29 ± 0.86

< 0.001

4.93 ± 0.83

4.61 ± 0.86

4.72 ± 0.89

4.66 ± 0.91

4.63 ± 0.86

0.001

Triglyceride (mmol/L), mean ± SD

1.09 ± 0.74

1.00 ± 0.64

1.14 ± 0.79

1.23 ± 0.98

1.36 ± 0.73

< 0.001

1.23 ± 0.74

1.00 ± 0.54

1.10 ± 0.87

1.15 ± 0.73

1.17 ± 0.93

< 0.001

High density lipoprotein cholesterol (mmol/L), mean ± SD

1.52 ± 0.36

1.51 ± 0.36

1.55 ± 0.36

1.58 ± 0.37

1.47 ± 0.34

0.001

1.52 ± 0.36

1.55 ± 0.36

1.51 ± 0.35

1.51 ± 0.35

1.47 ± 0.35

0.04

Low density lipoprotein cholesterol (mmol/L), mean ± SD

2.93 ± 0.83

2.69 ± 0.74

3.07 ± 0.82

3.29 ± 0.81

3.55 ± 0.82

< 0.001

3.16 ± 0.81

2.86 ± 0.81

2.99 ± 0.85

2.92 ± 0.88

2.92 ± 0.79

0.001

Fasting blood glucose (mmol/L), mean ± SD

5.28 ± 0.91

5.20 ± 0.89

5.33 ± 0.82

5.34 ± 0.78

5.58 ± 1.16

< 0.001

5.35 ± 0.96

5.28 ± 1.02

5.28 ± 0.76

5.28 ± 0.90

5.28 ± 0.84

0.94

Type 2 diabetes, n (%)

50 (2.4)

24 (1.9)

8 (2.6)

8 (2.8)

10 (3.9)

0.27

2 (1.3)

25 (3.2)

10 (2.0)

5 (1.3)

8 (2.9)

0.25

  1. SD standard deviation
  2. P values were calculated for continuous variables using analysis of variance or for categorical variables using the χ2 test