ACE2 SNPs | ACE (U/L) | Renin (pg/mL) | Ang I (ng/L) | ||||||
---|---|---|---|---|---|---|---|---|---|
 | Non-T2D | T2D | P value | Non-T2D | T2D | P value | Non-T2D | T2D | P value |
rs2074192 | Â | Â | Â | Â | Â | Â | Â | Â | Â |
CC | 40.3 ± 13.3 | 40.1 ± 15.6 | 0.936 | 33.2 ± 24.6 | 44.1 ± 18.9 | < 0.001 | 2.39 ± 0.84 | 2.68 ± 1.02 | 0.015 |
TT + CT | 40.9 ± 8.1 | 43.0 ± 14.4 | 0.137 | 32.7 ± 24.1 | 47.4 ± 23.4 | < 0.001 | 2.48 ± 0.85 | 2.68 ± 1.12 | 0.081 |
P value | 0.656 | 0.118 | Â | 0.868 | 0.189 | Â | 0.389 | 0.995 | Â |
rs4240157 | Â | Â | Â | Â | Â | Â | Â | Â | Â |
CC + CT | 38.9 ± 10.8 | 41.1 ± 15.4 | 0.243 | 34.5 ± 19.9 | 44.9 ± 21.4 | 0.001 | 2.37 ± 0.92 | 2.94 ± 0.97 | < 0.001 |
TT | 41.2 ± 10.2 | 41.9 ± 14.8 | 0.628 | 32.4 ± 25.5 | 46.5 ± 20.2 | < 0.001 | 2.47 ± 0.82 | 2.47 ± 1.11 | 0.949 |
P value | 0.117 | 0.682 |  | 0.501 | 0.539 |  | 0.449 | < 0.001 |  |
rs4646188 | Â | Â | Â | Â | Â | Â | Â | Â | Â |
CC + CT | 41.5 ± 11.4 | 37.6 ± 17.0 | 0.113 | 33.7 ± 24.1 | 45.2 ± 20.7 | 0.002 | 2.43 ± 0.69 | 2.32 ± 1.00 | 0.450 |
TT | 40.2 ± 9.7 | 42.7 ± 14.2 | 0.037 | 32.5 ± 24.4 | 45.9 ± 20.8 | < 0.001 | 2.45 ± 0.93 | 2.79 ± 1.07 | 0.001 |
P value | 0.306 | 0.017 | Â | 0.704 | 0.814 | Â | 0.788 | 0.002 | Â |
ACE2 SNPs | Ang II (ng/L) | ALD (ng/L) | Â | Â | Â | ||||
---|---|---|---|---|---|---|---|---|---|
 | Non-T2D | T2D | P value | Non-T2D | T2D | P value |  |  |  |
rs2074192 | Â | Â | Â | Â | Â | Â | Â | Â | Â |
CC | 116.6 ± 62.1 | 162.9 ± 55.0 | < 0.001 | 243.1 ± 73.8 | 224.7 ± 101.1 | 0.105 |  |  |  |
TT + CT | 126.2 ± 81.3 | 135.1 ± 46.5 | 0.232 | 235.1 ± 82.5 | 276.9 ± 110.8 | < 0.001 |  |  |  |
P value | 0.305 | < 0.001 |  | 0.419 | < 0.001 |  |  |  |  |
rs4240157 | Â | Â | Â | Â | Â | Â | Â | Â | Â |
CC + CT | 118.9 ± 65.6 | 168.7 ± 46.8 | < 0.001 | 233.2 ± 83.2 | 259.9 ± 107.5 | 0.085 |  |  |  |
TT | 123.7 ± 77.2 | 132.6 ± 51.7 | 0.193 | 239.6 ± 78.1 | 243.8 ± 110.2 | 0.688 |  |  |  |
P value | 0.655 | < 0.001 |  | 0.574 | 0.225 |  |  |  |  |
rs4646188 | Â | Â | Â | Â | Â | Â | Â | Â | Â |
CC + CT | 127.4 ± 85.5 | 117.5 ± 48.5 | 0.345 | 244.5 ± 76.4 | 222.2 ± 85.6 | 0.082 |  |  |  |
TT | 119.6 ± 67.2 | 158.3 ± 50.2 | < 0.001 | 234.3 ± 80.9 | 259.9 ± 114.0 | 0.011 |  |  |  |
P value | 0.406 | < 0.001 |  | 0.306 | 0.005 |  |  |  |  |