Table 3 Multivariable linear regression: Vascular measurements as a function of principal components and established risk factors of cardiovascular disease
From: IGFBP-1 and IGFBP-2 are associated with a decreased pulse-wave velocity in young, healthy adults
PWV (R2: 0.071) | AIX (R2: 0.041) | cIMT (R2: 0.019) | ||||
|---|---|---|---|---|---|---|
β (95% CI) | p | β (95% CI) | p | β (95% CI) | p | |
PC 1 | − 0.067 (− 0.15;0.020) | 0.17 | − 0.040 (− 0.13;0.052) | 0.66 | 0.079 (− 0.10;0.043) | 0.097 |
PC 2 | 0.013 (− 0.066;0.093) | 0.76 | 0.032 (− 0.051;0.12) | 0.48 | − 0.040 (− 0.077;0.069) | 0.35 |
PC 3 | 0.11 (0.027;0.20) | 0.023* | 0.065 (− 0.024;0.15) | 0.42 | − 0.013 (− 0.042;0.0.11) | 0.71 |
Age | 0.091 (0.051;0.13) | < 0.001* | 0.075 (0.032;0.12) | < 0.001* | 0.045 (0.011;0.080) | 0.041* |
Sex | 0.10 (− 0.11;0.29) | 0.38 | 0.098 (− 0.12;0.31) | 0.57 | − 0.041 (− 0.15;0.18) | 0.67 |
Body fat% | 0.10 (0.021;0.16) | 0.022* | 0.086 (− 0.0011;0.17) | 0.13 | − 0.0091 (− 0.014;0.13) | 0.78 |
Apo B/Apo A1 | 0.044 (− 0.043;0.13) | 0.33 | − 0.00075 (− 0.091;0.093) | 0.98 | 0.077 (− 0.052;0.088) | 0.11 |
HOMA− IR | − 0.067 (− 0.11;0.022) | 0.16 | − 0.059 (− 0.16;0.041) | 0.24 | − 0.036 (− 0.079;0.056) | 0.48 |
CRP | 0.012 (− 0.81;0.11) | 0.80 | 0.061 (− 0.038;0.16) | 0.23 | 0.015 (− 0.087;0.17) | 0.78 |