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Table 3 Comparisons of 2D speckle-tracking echocardiography-derived parameters between 3 groups of low-, moderate-, and high-risk CHA2DS2-VASc scores

From: Assessment of the ability of the CHA2DS2-VASc scoring system to grade left atrial function by 2D speckle-tracking echocardiography

Variable

Group

Unadjusted

P value

Comparison

Unadjusted post hoc

Adjusted post hocb

Ba (95% CI)

P value

Ba (95% CI)

P value

Low-Risk Score Group

(N = 34)

Moderate-Risk Score Group

(N = 83)

High-Risk Score Group

(N = 223)

LASr (%)

31.0 ± 5.0

29.8 ± 6.1

27.8 ± 6.9

0.004

Low-risk versus moderate-risk scores

1.1 (− 3.7 to 1.5)

0.389

1.4 (− 4.0 to 1.3)

0.313

Low-risk versus high-risk scores

3.2 (− 5.5 to − 0.8)

0.008

3.7 (− 6.1 to − 1.2)

0.004

Moderate-risk versus high-risk scores

2.1 (− 3.7 to − 0.5)

0.012

2.3 (− 4.0 to − 0.6)

0.007

pLASRr (1/s)

2.9 ± 0.6

2.9 ± 0.6

2.6 ± 0.7

0.009

Low-risk versus moderate-risk scores

0.0 (− 0.3 to 0.3)

0.881

0.0 (− 0.3 to 0.2)

0.775

Low-risk versus high-risk scores

0.3 (− 0.5 to 0.0)

0.044

0.4 (− .06 to − 0.1)

0.005

Moderate-risk versus high-risk scores

0.2 (− 0.4 to − 0.1)

0.007

0.3 (− 0.5 to − 0.1)

< 0.001

LAScd (%)

12.9 (9.4–15.1)

11.5 (9.1–13.8)

9.7 (7.1–12.5)

 < 0.001

Low-risk versus moderate-risk scores

0.9 (− 2.5 to 0.8)

0.297

1.1 (− 2.7 to 0.5)

0.191

Low-risk versus high-risk scores

2.6 (− 4.1 to − 1.1)

0.001

2.7 (− 4.2 to − 1.1)

0.001

Moderate-risk versus high-risk scores

1.7 (− 2.8 to − 0.7)

0.001

1.6 (− 2.6 to − 0.6)

0.003

pLASRcd (1/s)

2.8 (2.4–3.6)

2.6 (2.2–3.0)

2.1 (1.6–2.7)

 < 0.001

Low-risk versus moderate-risk scores

0.4 (− 0.7 to − 0.1)

0.010

0.4 (− 0.8 to − 0.1)

0.005

Low-risk versus high-risk scores

0.8 (− 1.1 to − 0.5)

< 0.001

0.8 (− 1.1 to − 0.5)

< 0.001

Moderate-risk versus high-risk scores

0.4 (− 0.6 to − 0.2)

< 0.001

0.4 (− 0.6 to − 0.2)

< 0.001

LASct (%)

18.4 ± 3.6

18.1 ± 4.2

17.8 ± 4.9

0.752

Low-risk versus moderate-risk scores

0.3 (− 2.1 to 1.6)

0.780

0.3 (− 2.1 to 1.5)

0.770

Low-risk versus high-risk scores

0.6 (− 2.2 to 1.1)

0.513

1.0 (− 2.7 to 0.7)

0.256

Moderate-risk versus high-risk scores

0.4 (− 1.5 to 0.8)

0.543

0.7 (− 1.9 to 0.4)

0.225

pLASRct (1/s)

4.3 ± 0.9

4.2 ± 1.1

4.1 ± 1.3

0.499

Low-risk versus moderate-risk scores

0.1 (− 0.6 to 0.40)

0.794

0.1 (− 0.6 to 0.4)

0.673

Low-risk versus high-risk scores

0.2 (− 0.6 to 0.2)

0.359

0.4 (− 0.8 to 0.1)

0.087

Moderate-risk versus high-risk scores

0.2 (− 0.5 to 0.2)

0.322

0.3 (− 0.6 to 0.0)

0.063

  1. aAbsolute value of B is presented
  2. bAdjusted according to systolic blood pressure, heart rate, hemoglobin levels, low-density lipoprotein levels, cigarette smoking, left circumflex artery stenosis, single-vessel disease, obesity, and nitrate use
  3. CI, confidence interval; LAScd, left atrial longitudinal strain during the conduit phase; LASct, Left atrial longitudinal strain during the contraction phase; LASr, Left atrial longitudinal strain during the reservoir phase; pLASRcd, peak left atrial longitudinal strain rate during the conduit phase; pLASRct, Peak left atrial longitudinal strain rate during the contraction phase; pLASRr, peak left atrial longitudinal strain rate during the reservoir phase
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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