Table 1 Clinical and laboratory data of the 3 groups of low-, moderate-, and high-risk CHA2DS2-VASc scores
Variable | Group | P value | ||
|---|---|---|---|---|
Low-Risk Score (N = 34) | Moderate-Risk Score (N = 83) | High-Risk Score (N = 223) | ||
Clinical data | Â | Â | Â | Â |
Age (y) | 55 ± 6 | 59 ± 7c | 64 ± 9a,b | < 0.001 |
Age < 65 | 34 (100) | 68 (82) | 113 (51) | < 0.001 |
65 ≤ Age < 75 | 0(0) | 15 (18) | 83 (37) |  |
Age ≥ 75 | 0 (0) | 0(0) | 27 (12) |  |
Female sex (%) | 4 (12) | 17 (21) | 61 (27) | 0.095 |
Body mass index (kg/m2) | 27.9 ± 4.5 | 28.3 ± 4.6 | 27.4 ± 4.0 | 0.289 |
Body surface area (m2) | 1.9 ± 0.2 | 1.8 ± 0.2 | 1.8 ± 0.2a,b | 0.002 |
Obesity (%) | 8 (24) | 30 (36) | 50 (22) | 0.049 |
Hypertension (%) | 0 (0) | 35 (42) | 167 (75) | < 0.001 |
Diabetes (%) | 0 (0) | 22 (27) | 149 (67) | < 0.001 |
Stroke (%) | 0 (0) | 0(0) | 27 (12) | < 0.001 |
Vascular disease (peripheral vascular disease, prior myocardial infarction, aortic plaque) (%) | 0 (0) | 4 (5) | 26 (12) | 0.028 |
History of myocardial infarction (%) | 0 (0) | 4 (5) | 26 (12) | 0.028 |
Cigarette smoking (%) | 16 (47) | 34 (41) | 72 (32) | 0.133 |
History of aspirin use (%) | 33 (97) | 76 (92) | 208 (93) | 0.561 |
History of ACEI/ARB use (%) | 12 (35) | 38 (46) | 146 (66) |  < 0.001 |
History of beta-blocker use (%) | 24 (71) | 55 (66) | 170 (76) | 0.202 |
History of calcium-channel blocker use (%) | 1 (2.9) | 8 (10) | 39 (18) | 0.031 |
History of nitrate use (%) | 28 (82) | 55 (66) | 145 (65) | 0.132 |
History of statin use (%) | 31 (91) | 72 (87) | 181 (81) | 0.226 |
History of diuretic use (%) | 0 (0) | 5 (6) | 42 (19) | 0.001 |
History of oral antidiabetic use (%) | 0 (0) | 16 (19) | 110 (49) |  < 0.001 |
History of insulin use (%) | 0 (0) | 5 (6) | 49 (22) |  < 0.001 |
Left anterior descending artery (%) | 34 (100) | 83 (100) | 223 (100) |  > 0.999 |
Left circumflex artery (%) | 26 (77) | 70 (84) | 202 (91) | 0.038 |
Right coronary artery (%) | 30 (88) | 74 (89) | 203 (91) | 0.808 |
Single-vessel disease (%) | 3 (9) | 4 (5) | 4 (2) | 0.040 |
Double-vessel disease (%) | 6 (18) | 14 (17) | 33 (15) | 0.853 |
Triple-vessel disease (%) | 25 (74) | 65 (78) | 186 (83) | 0.293 |
Heart rate (bpm) | 64 ± 10 | 67 ± 11 | 70 ± 12a | 0.004 |
Systolic blood pressure (mm Hg) | 124 ± 12 | 125 ± 15 | 129 ± 18 | 0.083 |
Diastolic blood pressure (mm Hg) | 78 ± 8 | 78 ± 10 | 76 ± 11 | 0.356 |
Laboratory data | Â | Â | Â | Â |
Fasting blood sugar (mg/dL) | 97 ± 17 | 113 ± 41c | 123 ± 42a | 0.001 |
Creatinine (mg/dL) | 1.1 ± 0.2 | 1.1 ± 0.2 | 1.1 ± 0.2 | 0.620 |
Hemoglobin (g/dL) | 14.8 ± 1.1 | 14.2 ± 1.7 | 13.9 ± 1.6a | 0.009 |
Triglyceride (mg/dL) | 153 (103–200) | 145 (117–192) | 142 (108–195) | 0.790 |
Cholesterol (mg/dL) | 163 ± 50 | 149 ± 41 | 141 ± 39a | 0.009 |
High-density lipoprotein (mg/dL) | 37 (30–41) | 35 (30–39) | 36 (31–41) | 0.641 |
Low-density lipoprotein (mg/dL) | 95 (71–126) | 81 (66–109) | 77 (62–99)a | 0.012 |