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Fig. 5 | BMC Cardiovascular Disorders

Fig. 5

From: Diabetes impairs the protective effects of sevoflurane postconditioning in the myocardium subjected to ischemia/ reperfusion injury in rats: important role of Drp1

Fig. 5

Cardioprotective effect of SevP was restored by Drp1 inhibitior mdivi-1 in diabetic rats subjected to myocardial I/R injury. a Infarct size expressed as a percentage of IS/AAR and plasma levels of CK-MB and cTnI assessed by ELISA kit. b MDA levels and total SOD activity assessed by detection kits. c Representative electron microscopic images of mitochondrial ultrastructure of myocardium subjected to ischemia/reperfusion (magnification ×15,000, scale bar: 1µm). n = 8 per group. *P: 0.001 versus DI/R group; #P: 0.001 versus DSev group; **P: 0.001 versus DI/R + Mdivi-1group

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