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Table 3 Multivariate analysis of variables associated with in-hospital mortality in patients with STEMI

From: Predictive value of elevated alanine aminotransferase for in-hospital mortality in patients with acute myocardial infarction

Variables

Survivors (n = 35)

Non-survivors (n = 120)

P value

AOR (95% CI)

Age ≥ 65 year, n (%)

151 (42.7)

97 (80.8)

 < 0.001

4.668 (2.684–8.117)

Male, n (%)

256 (72.3)

71(59.2)

0.542

0.848 (0.498–1.441)

DM, n (%)

64 (25.4)

45 (37.5)

0.610

1.161 (0.654–2.062)

Smoking, n (%)

212 (59.9)

58 (48.3)

0.864

1.046 (0.627–1.743)

FPG ≥ 6.1 mmol/L, n (%)

154 (43.5)

76 (63.3)

0.005

2.010 (1.236–3.267)

TG ≥ 1.8 mmol/L, n (%)

134 (37.9)

31 (25.8)

0.208

0.699 (0.400–1.221)

TC ≥ 6.6 mmol/L, n (%)

19 (5.4)

5 (4.2)

0.930

0.948 (0.288–3.117)

AST ≥ 2 ULN, n (%)

230 (65.0)

76 (63.3)

0.529

0.832 (0.470–1.474)

ALT ≥ 2 ULN, n (%)

74 (15.6)

27 (22.5)

0.041

1.915 (1.028–3.565)

GGT ≥ 2 ULN, n (%)

35 (0.9)

18 (15.0)

0.287

1.502 (0.710–3.178)

DD ≥ 400 ng/mL, n (%)

103 (29.1)

75 (62.5)

0.010

1.937 (1.170–3.194)

Tn I ≥ 2.5 ng/mL, n (%)

201 (56.8)

77 (64.2)

0.952

0.984 (0.572–1.692)

Fib ≥ 3.5 g/L, n (%)

163 (46.0)

76 (63.3)

0.017

1.810 (1.113–2.944)

eGFR (mL/min/1.73 m2) < 90, n (%)

95 (26.8)

70 (58.3)

0.017

1.834 (1.112–3.023)

  1. Age, sex, DM, smoking history, FPG, TC, triglycerides, AST, ALT, GGT, Tn I, D-dimer, fibrinogen, and eGFR were included in the multivariate logistic regression analysis
  2. ALT, alanine aminotransferase; AOR, adjusted odds ratio; AST, aspartate aminotransferase; CI, confidence interval; DM, diabetes mellitus; eGFR, estimated glomerular filtration rate; FPG, fasting plasma glucose; GGT, γ-glutamyl transpeptidase; NSTEMI, non–ST-segment elevation myocardial infarction; STEMI, ST-segment elevation myocardial infarction; T-Bil, total bilirubin; TC, total cholesterol; Tn I, cardiac troponin I; ULN, upper limit of normal