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Table 2 Multivariate analysis of variables associated with in-hospital mortality in all study patients

From: Predictive value of elevated alanine aminotransferase for in-hospital mortality in patients with acute myocardial infarction

Variable

Survivors (n = 520)

Non-survivors (n = 192)

P value

AOR (95% CI)

Age (y)

  

 < 0.001

4.320 (2.687–6.947)

 < 65, n (%)

283 (54.4)

31 (16.1)

  

 ≥ 65, n (%)

237 (45.6)

161 (83.9)

  

Sex

  

0.298

0.795 (0.517–1.224)

 Female, n (%)

149 (28.7)

83 (43.2)

  

 Male, n (%)

371 (71.3)

109 (56.8)

  

DM

  

0.229

1.317 (0.841–2.063)

 No, n (%)

387 (74.4)

109 (56.8)

  

 Yes, n (%)

133 (25.6)

83(43.2)

  

History of smoking

  

0.364

1.317 (0.798–1.853)

 No, n (%)

208 (40.0)

96 (50.0)

  

 Yes, n (%)

312 (60.0)

96 (50.0)

  

FPG (mmol/L)

  

 < 0.001

2.319 (1.564–3.438)

 < 6.1, n (%)

302 (58.1)

65 (33.9)

  

 ≥ 6.1, n (%)

218 (41.9)

127 (66.1)

  

Triglycerides (mmol/L)

  

0.184

0.739 (0.472–1.155)

 < 1.8, n (%)

326 (62.7)

142 (74.0)

  

 ≥ 1.8, n (%)

194 (37.3)

50 (26.0)

  

TC (mmol/L)

  

0.689

1.194 (0.502–2.843)

 < 6.6, n (%)

490 (94.2)

180 (93.7)

  

 ≥ 6.6, n (%)

30 (5.8)

12 (6.3)

  

AST (U/L)

  

0.764

1.075 (0.671–1.722)

 < 2 ULN, n (%)

237 (45.6)

79 (41.1)

  

 ≥ 2 ULN, n (%)

283 (54.4)

113 (58.9)

  

ALT (U/L)

  

0.002

2.240 (1.331–3.771)

 < 2 ULN, n (%)

432 (83.1)

140 (72.9)

  

 ≥ 2 ULN, n (%)

88 (16.9)

52 (27.1)

  

GGT (U/L)

  

0.643

1.161 (0.618–2.182)

 < 2 ULN, n (%)

468 (90.0)

163 (84.9)

  

 ≥ 2 ULN, n (%)

52 (10.0)

29 (15.1)

  

D-dimer (ng/mL)

  

 < 0.001

2.117 (1.407–3.184)

 < 400, n (%)

374 (71.9)

67 (34.9)

  

 ≥ 400, n (%)

146 (28.1)

125 (65.1)

  

Tn I (ng/mL)

  

0.736

0.929 (0.604–1.429)

 < 2.5, n (%)

266 (51.2)

87 (45.3)

  

 ≥ 2.5, n (%)

254 (48.8)

105 (54.7)

  

Fibrinogen (g/L)

  

0.020

1.601 (1.077–2.380)

 < 3.5, n (%)

289 (55.6)

73 (38.0)

  

 ≥ 3.5, n (%)

231 (44.4)

119 (62.0)

  

eGFR (mL/min/1.73 m2)

  

 < 0.001

2.279 (1.519–3.419)

 ≥ 90, n (%)

373 (71.7)

65 (33.9)

  

 < 90, n (%)

147 (28.3)

127 (66.1)

  
  1. Age, sex, DM, smoking history, FPG, TC, triglycerides, AST, ALT, GGT, Tn I, D-dimer, fibrinogen, and eGFR were included in the multivariate logistic regression analysis
  2. ALT, alanine aminotransferase; AOR, adjusted odds ratio; AST, aspartate aminotransferase; CI, confidence interval; DM, diabetes mellitus; eGFR, estimated glomerular filtration rate; FPG, fasting plasma glucose; GGT, γ-glutamyl transpeptidase; NSTEMI, non–ST-segment elevation myocardial infarction; STEMI, ST-segment elevation myocardial infarction; T-Bil, total bilirubin; TC, total cholesterol; Tn I, cardiac troponin I; ULN, upper limit of normal