Variables | Vildagliptin group (n = 10) | Control group (n = 10) | p Value |
---|---|---|---|
Men, % | 100 | 80 | 0.474 |
Age, years | 65.9 ± 10.6 | 68.3 ± 8.1 | 0.820 |
BMI, kg/m2 | 24.0 ± 4.0 | 24.0 ± 4.5 | 0.909 |
Smoker, % | 70 | 40 | 0.133 |
Familial history, % | 10 | 10 | 1.000 |
Stable angina, % | 100.0 | 100.0 | |
Revascularization vessel, % | 0.409 | ||
Right coronary artery, % | 31.8 | 34.6 | |
Left main coronary trunk, % | 18.2 | 7.7 | |
Left anterior descending coronary artery, % | 31.8 | 34.6 | |
Left circumflex coronary artery, % | 18.2 | 23.1 | |
Medication, % | |||
Beta blocker, % | 70.0 | 50.0 | 0.649 |
ACE-I/ARB, % | 50.0 | 50.0 | 1.000 |
Statin, % | 90.0 | 100.0 | 1.000 |
Other oral DM drugs, % (except DPP-4 inhibitors) | 0.0 | 0.0 | |
Insulin, % | 0.0 | 0.0 | |
Prasugrel, % | 40.0 | 60.0 | 0.656 |
Clopidogrel, % | 60.0 | 40.0 | 0.656 |
Aspirin, % | 100.0 | 100.0 | 0 |
Laboratory data | |||
LDL cholesterol, mg/dl | 84.0 ± 14.3 | 82.9 ± 27 | 0.791 |
HDL cholesterol, mg/dl | 47.4 ± 14.8 | 41.5 ± 9.8 | 0.289 |
Triglyceride, mg/dl | 118.4 ± 52.1 | 131.6 ± 77.9 | 0.939 |
Creatinine, mg/dl | 0.8 ± 0.1 | 0.9 ± 0.3 | 1.000 |
1,5 AG, μg/ml | 19.9 ± 4.1 | 22.0 ± 4.1 | 0.377 |
HbA1c (NGSP), % | 5.9 ± 0.3 | 5.9 ± 0.4 | 0.845 |
HOMA R | 1.5 ± 5.7 | 1.5 ± 0.6 | 0.909 |
CRP, mg/dl | 0.2 ± 0.4 | 0.2 ± 0.2 | 0.879 |
75 g OGTT | |||
Fast glucose, mg/dl | 97.2 ± 9.0 | 94.2 ± 11.9 | 0.471 |
2-h glucose, mg/dl | 185.7 ± 36.6 | 169.5 ± 20.5 | 0.405 |
Fast IRI, μU/ml | 6.6 ± 3.5 | 6.3 ± 2.7 | 1.000 |
2-h IRI, μU/ml | 114.1 ± 80.3 | 101.3 ± 75.6 | 0.791 |