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Table 1 Baseline patient and lesion characteristics

From: The impact of vildagliptin on the daily glucose profile and coronary plaque stability in impaired glucose tolerance patients with coronary artery disease: VOGUE—A multicenter randomized controlled trial

Variables

Vildagliptin group (n = 10)

Control group (n = 10)

p Value

Men, %

100

80

0.474

Age, years

65.9 ± 10.6

68.3 ± 8.1

0.820

BMI, kg/m2

24.0 ± 4.0

24.0 ± 4.5

0.909

Smoker, %

70

40

0.133

Familial history, %

10

10

1.000

Stable angina, %

100.0

100.0

 

Revascularization vessel, %

  

0.409

 Right coronary artery, %

31.8

34.6

 

 Left main coronary trunk, %

18.2

7.7

 

 Left anterior descending coronary artery, %

31.8

34.6

 

 Left circumflex coronary artery, %

18.2

23.1

 

Medication, %

 Beta blocker, %

70.0

50.0

0.649

 ACE-I/ARB, %

50.0

50.0

1.000

 Statin, %

90.0

100.0

1.000

 Other oral DM drugs, % (except DPP-4 inhibitors)

0.0

0.0

 

 Insulin, %

0.0

0.0

 

 Prasugrel, %

40.0

60.0

0.656

 Clopidogrel, %

60.0

40.0

0.656

 Aspirin, %

100.0

100.0

0

Laboratory data

 LDL cholesterol, mg/dl

84.0 ± 14.3

82.9 ± 27

0.791

 HDL cholesterol, mg/dl

47.4 ± 14.8

41.5 ± 9.8

0.289

 Triglyceride, mg/dl

118.4 ± 52.1

131.6 ± 77.9

0.939

 Creatinine, mg/dl

0.8 ± 0.1

0.9 ± 0.3

1.000

 1,5 AG, μg/ml

19.9 ± 4.1

22.0 ± 4.1

0.377

 HbA1c (NGSP), %

5.9 ± 0.3

5.9 ± 0.4

0.845

 HOMA R

1.5 ± 5.7

1.5 ± 0.6

0.909

 CRP, mg/dl

0.2 ± 0.4

0.2 ± 0.2

0.879

75 g OGTT

 Fast glucose, mg/dl

97.2 ± 9.0

94.2 ± 11.9

0.471

 2-h glucose, mg/dl

185.7 ± 36.6

169.5 ± 20.5

0.405

 Fast IRI, μU/ml

6.6 ± 3.5

6.3 ± 2.7

1.000

 2-h IRI, μU/ml

114.1 ± 80.3

101.3 ± 75.6

0.791

  1. Mean ± standard deviation (n) for continuous variables; frequency count (%) for categorical variables 1,5 AG = 1,5 anhydroglucitol; 75 g OGTT = 75 g oral glucose tolerance test; ACE-I = angiotensin converting enzyme-inhibitor; ARB = angiotensin II receptor blocker; BMI = body mass index; CRP = C-reactive protein; DM = diabetes mellitus; DPP-4 = dipeptidyl peptidase-4; HbA1c = glycated hemoglobin; HDL = high-density lipoprotein; HOMA R = homeostasis model assessment ratio; IRI = immunoreactive insulin; LDL = low-density lipoprotein; NGSP = national glycohemoglobin standardization program