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Table 5 The genotype distributions of CYP2C9 and AGTR1 in different grades of Han Chinese hypertensive patients and normotensive controls

From: Distributive characteristics of the CYP2C9 and AGTR1 genetic polymorphisms in Han Chinese hypertensive patients: a retrospective study

Genotype

Normotensive % (N)

The grades of hypertension % (N)

p value

Grade 1

Grade 2

Grade 3

CYP2C9*1/*1

96.03% (121)

96.43% (135)

94.13% (577)

92.74% (1545)

0.44a 0.48b

CYP2C9*1/*3

3.97% (5)

3.57% (5)

5.71% (35)

6.90% (115)

CYP2C9*3/*3

0.00% (0)

0.00% (0)

0.16% (1)

0.36% (6)

AGTR1-AA

92.06% (116)

87.86% (123)

88.74% (544)

91.24% (1520)

0.20 a 0.19 b

AGTR1-AC

7.14% (9)

12.14% (17)

11.09% (68)

8.40% (140)

AGTR1-CC

0.79% (1)

0.00% (0)

0.16% (1)

0.36% (6)