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Table 2 Demographic and biochemical data of pCAD and control groups

From: Effect of ABCA1 promoter methylation on premature coronary artery disease and its relationship with inflammation

Characteristics Control group
(n = 90)
PCAD group
(n = 90)
t/χ2/Z P value
Men (%) 54 (60.0) 61 (67.8) 1.180 0.277
Age (years) 53.43 ± 3.23 52.13 ± 5.35 1.975 0.051
BMI (kg/m2) 23.98 ± 1.34 24.98 ± 1.25 5.163 0.0005
Waist circumference (cm) 79.6 ± 3.50 80.96 ± 3.73 2.516 0.013
Cigarette smoking (%) 31 (34.4) 32 (35.6) 0.024 0.876
SBP (mmHg) 130.0 (125.1–145.5) 135.5 (130.0–150.0) 1.153 0.249
DBP (mmHg) 80.0 (75.0–88.5) 82.5 (75.0–90.0) 1.010 0.313
HDL-C (mmol/L) 1.19 ± 0.27 0.86 ± 0.18 9.477  < 0.001
LDL-C (mmol/L) 2.87 ± 0.82 3.00 ± 0.98 1.320 0.189
TC (mmol/L) 4.23 ± 0.84 4.41 ± 1.09 1.239 0.217
TG (mmol/L) 1.88 ± 1.67 2.11 ± 1.40 0.998 0.320
Hcy (μmol/L) 13.84 ± 3.15 14.58 ± 4.17 1.337 0.183
Fasting glucose (mmol/L) 5.55 (5.08–6.68) 5.90 (4.90–7.88) 0.780 0.435
HbA1c (%) 5.70 (5.20–6.33) 6.25 (5.40–7.13) 2.770 0.006
Diabetes mellitus (%) 26 (28.9) 41 (45.6) 5.349 0.021
Hypertension (%) 40 (44.4) 50 (55.6) 2.222 0.136
CRP (mg/L) 4.47 ± 3.06 7.44 ± 3.63 5.925  < 0.001
cfDNA/NETs (ng/mL) 9.93 ± 10.73 24.40 ± 13.18 8.064  < 0.001
IL-1β (pg/mL) 47.66 ± 14.77 57.74 ± 12.55 4.933  < 0.001
  1. Variables are presented as means ± standard deviations, median (interquartile spacing), or percentages. BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TC, total cholesterol; TG, triglycerides; Hcy, homocysteine; HbA1c, glycated haemoglobin; CRP, C-reactive protein; cfDNA/NETs, circulating free DNA/Neutrophil extracellular traps; IL-1β, interleukin-1β