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Table 2 Demographic and biochemical data of pCAD and control groups

From: Effect of ABCA1 promoter methylation on premature coronary artery disease and its relationship with inflammation

Characteristics

Control group

(n = 90)

PCAD group

(n = 90)

t/χ2/Z

P value

Men (%)

54 (60.0)

61 (67.8)

1.180

0.277

Age (years)

53.43 ± 3.23

52.13 ± 5.35

1.975

0.051

BMI (kg/m2)

23.98 ± 1.34

24.98 ± 1.25

5.163

0.0005

Waist circumference (cm)

79.6 ± 3.50

80.96 ± 3.73

2.516

0.013

Cigarette smoking (%)

31 (34.4)

32 (35.6)

0.024

0.876

SBP (mmHg)

130.0 (125.1–145.5)

135.5 (130.0–150.0)

1.153

0.249

DBP (mmHg)

80.0 (75.0–88.5)

82.5 (75.0–90.0)

1.010

0.313

HDL-C (mmol/L)

1.19 ± 0.27

0.86 ± 0.18

9.477

 < 0.001

LDL-C (mmol/L)

2.87 ± 0.82

3.00 ± 0.98

1.320

0.189

TC (mmol/L)

4.23 ± 0.84

4.41 ± 1.09

1.239

0.217

TG (mmol/L)

1.88 ± 1.67

2.11 ± 1.40

0.998

0.320

Hcy (μmol/L)

13.84 ± 3.15

14.58 ± 4.17

1.337

0.183

Fasting glucose (mmol/L)

5.55 (5.08–6.68)

5.90 (4.90–7.88)

0.780

0.435

HbA1c (%)

5.70 (5.20–6.33)

6.25 (5.40–7.13)

2.770

0.006

Diabetes mellitus (%)

26 (28.9)

41 (45.6)

5.349

0.021

Hypertension (%)

40 (44.4)

50 (55.6)

2.222

0.136

CRP (mg/L)

4.47 ± 3.06

7.44 ± 3.63

5.925

 < 0.001

cfDNA/NETs (ng/mL)

9.93 ± 10.73

24.40 ± 13.18

8.064

 < 0.001

IL-1β (pg/mL)

47.66 ± 14.77

57.74 ± 12.55

4.933

 < 0.001

  1. Variables are presented as means ± standard deviations, median (interquartile spacing), or percentages. BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TC, total cholesterol; TG, triglycerides; Hcy, homocysteine; HbA1c, glycated haemoglobin; CRP, C-reactive protein; cfDNA/NETs, circulating free DNA/Neutrophil extracellular traps; IL-1β, interleukin-1β