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Table 5 Univariate and multivariate regression for haplotypes of HPA1-3 polymorphisms

From: Association of human platelet alloantigens encoding gene polymorphisms with the risk of Coronary artery disease in Iranian patients

 

Univariate regression

Multivariate regression

Z-score

P value

OR (95% CI)

Z-score

P value

OR (95% CI)a

1a/2a/3a

–

–

1.00

–

–

1.00

1a/2a/3b

− 1.321

0.186

0.772 (0.53–1.13)

− 0.750

0.454

0.838 (0.53–1.33)

1a/2b/3a

− 0.385

0.700

0.864 (0.41–1.81)

− 0.769

0.442

0.698 (0.28–1.75)

1a/2b/3b

1.052

0.293

1.653 (0.65–4.22)

0.118

0.905

1.075 (0.33–3.54)

1b/2a/3a

− 1.782

0.075

0.511 (0.24–1.07)

− 0.943

0.345

0.645 (0.26–1.60)

1b/2a/3b

1.259

0.208

2.254 (0.64–4.99)

2.436

0.015

2.792 (1.46–8.60)

BMI (kg/cm2)

–

–

–

0.251

0.094

1.058 (0.98–1.08)

Sys.BP (mmHg)

–

–

–

2.333

0.013

1.021 (1.00–1.04)

FBS (mg/dl)

–

–

–

3.571

0.000

1.040 (1.03–1.05)

Total.Chol(mg/dl)

–

–

–

3.306

0.000

2.008 (1.00–2.02)

LDL (mg/dl)

–

–

–

− 4.633

0.001

1.967 (0.96–1.98)

TG (mg/dl)

–

–

–

2.817

0.000

1.017 (1.01–1.02)

  1. OR odds ratio, CI confidence interval, BP blood pressure, BMI body mass index, FBS fasting blood sugar, TG trigliserid, LDL low-density lipoprotein
  2. aAdjusted for age, BMI, systolic and diastolic BP, FBS, total cholesterol, TG, and LDL concentrations
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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