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Table 5 Univariate and multivariate regression for haplotypes of HPA1-3 polymorphisms

From: Association of human platelet alloantigens encoding gene polymorphisms with the risk of Coronary artery disease in Iranian patients

  Univariate regression Multivariate regression
Z-score P value OR (95% CI) Z-score P value OR (95% CI)a
1a/2a/3a 1.00 1.00
1a/2a/3b − 1.321 0.186 0.772 (0.53–1.13) − 0.750 0.454 0.838 (0.53–1.33)
1a/2b/3a − 0.385 0.700 0.864 (0.41–1.81) − 0.769 0.442 0.698 (0.28–1.75)
1a/2b/3b 1.052 0.293 1.653 (0.65–4.22) 0.118 0.905 1.075 (0.33–3.54)
1b/2a/3a − 1.782 0.075 0.511 (0.24–1.07) − 0.943 0.345 0.645 (0.26–1.60)
1b/2a/3b 1.259 0.208 2.254 (0.64–4.99) 2.436 0.015 2.792 (1.46–8.60)
BMI (kg/cm2) 0.251 0.094 1.058 (0.98–1.08)
Sys.BP (mmHg) 2.333 0.013 1.021 (1.00–1.04)
FBS (mg/dl) 3.571 0.000 1.040 (1.03–1.05)
Total.Chol(mg/dl) 3.306 0.000 2.008 (1.00–2.02)
LDL (mg/dl) − 4.633 0.001 1.967 (0.96–1.98)
TG (mg/dl) 2.817 0.000 1.017 (1.01–1.02)
  1. OR odds ratio, CI confidence interval, BP blood pressure, BMI body mass index, FBS fasting blood sugar, TG trigliserid, LDL low-density lipoprotein
  2. aAdjusted for age, BMI, systolic and diastolic BP, FBS, total cholesterol, TG, and LDL concentrations