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Table 1 Baseline characteristics of the study population

From: Dysregulation of serum miR-361-5p serves as a biomarker to predict disease onset and short-term prognosis in acute coronary syndrome patients

Features Total individuals (n = 262) Healthy controls (n = 66) SCHD patients (n = 78) ACS patients (n = 118) P1 value P2 value P3 value
Age (years) 65.0 ± 9.7 65.0 ± 11.2 63.8 ± 7.9 65.6 ± 9.7 0.759 0.912 0.430
Gender, male (%) 157 (59.9%) 40 (60.6) 49 (62.8) 68 (57.6) 0.785 0.694 0.468
BMI (kg/m2) 25.0 ± 2.7 24.7 ± 2.3 25.4 ± 3.2 25.0 ± 2.7 0.324 0.792 0.603
TC (mM) 4.7 ± 0.8 4.6 ± 0.5 4.5 ± 0.6 5.0 ± 0.8 0.935 0.006 0.001
TG (mM) 1.8 ± 0.6 1.6 ± 0.6 1.8 ± 0.5 1.8 ± 0.6 0.512 0.087 0.594
HDL-C (mM) 1.2 ± 0.3 1.5 ± 0.2 1.2 ± 0.2 1.2 ± 0.3 < 0.001 < 0.001 0.979
LDL-C (mM) 2.7 ± 0.6 2.5 ± 0.7 2.6 ± 0.4 2.8 ± 0.6 0.247 0.002 0.173
Hypertension (%) 85 (32.4%) 19 (28.8) 24 (30.8) 42 (35.6) 0.796 0.347 0.484
Diabetes (%) 81 (30.9%) 17 (25.8) 25 (32.1) 39 (33.1) 0.408 0.302 0.884
WBC (× 109/L) 8.0 ± 2.6 6.3 ± 1.4 7.6 ± 1.8 9.1 ± 2.6 0.004 < 0.001 < 0.001
cTnI (ng/mL) 0.8 ± 0.9 0.09 ± 0.1 0.2 ± 0.2 1.6 ± 1.2 < 0.001 < 0.001 < 0.001
Gensini score 47.5 ± 19.5 58.6 ± 24.4 0.002
  1. P1: SCHD patients vs. healthy controls; P2: ACS patients vs. healthy controls; P3: ACS patients vs. SCHD patients
  2. SCHD stable coronary heart disease, ACS acute coronary syndrome, BMI body mass index, TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, WBC white blood cell, cTnI cardiac troponin I