Fig. 1

a ROC curve describing the predictive ability for models A (univariable), B and C (multivariable) for IHD. Model A: Framingham risk score. Model B: Clinical risk factors (hypertension, cholesterol, HDL). Model C: Clinical risk factors + hs-TnT. Model C CV: Cross-validation model for Model C. ROC = receiver operating characteristic curve; IHD = ischemic heart disease; CV = cross-validation; HDL = high-density lipoprotein; hs-TNT = high sensitivity troponin-T. b Time-dependent AUCs describing the predictive ability for models A (univariable), B and C (multivariable) for IHD continuously over follow-up time. AUC = area under the curve; IHD = ischemic heart disease; PCI = percutaneous coronary intervention; CABG = coronary artery bypass graft