Table 3 Laboratory parameters of patients with sustained, intermittent and non-PPI users

N

201

188

249

Laboratory parameters

Creatinine (mg/dL)

104.5 ± 70.8

111.3 ± 97.8

103.2 ± 56.7

Glucose (mmol/L)

5.5 ± 1.8

5.9 ± 2.4

5.7 ± 1.9

Total cholesterol (mmol/L)

4.22 (3.51, 5.11)

4.48 (3.81, 5.42)

4.47 (3.65, 5.25)

HDL-C (mmol/L)

1.07 (0.90, 1.32)

1.08 (0.89, 1.29)

1.06 (0.90, 1.26)

LDL-C (mmol/L)

2.46 (1.98, 3.12)

2.64 (2.14, 3.29)

2.59 (2.08, 3.19)

Triglycerides (mmol/L)

1.20 (0.94, 1.86)

1.38 (0.94, 2.04)

1.45 (1.05, 2.09)

Uric acid (µmol/L)

368.0 (311.0, 446.0)

393.0 (319.0, 477.0)

391.0 (329.0, 469.5)

ALT (U/L)

21.0 (15.0, 33.0)

20.0 (14.0, 35.5)

21.0 (15.0, 32.0)

AST (U/T)

23.0 (18.0, 38.0)

21.0 (18.0, 34.5)

23.0 (18.0, 29.0)

CK (U/L)

94.0 (64.0, 162.0)

87.0 (62.5, 136.0)

90.5 (65.0, 168.5)

CK-MB (U/L)

14.0 (11.0, 20.0)

14.0 (11.0, 19.0)

13.0 (11.0, 17.0)

hs-CRP (mg/L)

7156.0 (5888.0, 8098.0)

7439.0 (6282.0, 8259.0)

7544.5 (6269.8, 8507.0)

HbAlc (%)

6.0 (5.6, 6.6)

6.0 (5.6, 7.1)

6.1 (5.6, 7.1)

NT-proBNP

126.3 (55.1, 674.7)

151.0 (66.4, 587.6)

159.9 (63.2, 697.5)

TnT-HS

7.4 (4.4, 50.7)

13.2 (5.0, 398.0)

11.1 (5.4, 67.3)

Hb (g/L)

131.5 ± 19.1

129.4 ± 18.7

134.7 ± 22.5

Platelet count (× 10⁹/L)

221.6 ± 60.8

235.5 ± 64.3

221.9 ± 62.2

CYP2C19 genotypes (%)

110

111

115

 EM

31.8

39.6

42.6

 IM

50.0

45.0

40.9

 PM

18.2

15.3

16.5