Table 4 Attenuation of the male-to-female hazard ratio by different groups of variables in proportional hazard models

(A) CVD

Smoking

2.431*** (1.762–3.355)

2.405*** (1.727–3.349)

Obesity

1.041 (0.785–1.361)

1.172 (0.878–1.565)

Grade II hypertension

1.264 (0.959–1.667)

1.237 (0.932–1.642)

Cholesterol

0.931 (0.704–1.230)

0.934 (0.705 – 1.236)

TG

1.108 (0.671–1.828)

1.192 (0.721 – 1.969)

Reported MI

1.470* (1.062–2.034)

1.375 (0.988–1.912)

Reported stroke

1.747** (1.236–2.470)

1.823** (1.287–2.581)

ST depression

1.506* (1.071–2.117)

1.473* (1.040–2.086)

VPC ≥ 10/h

1.381* (1.034–1.844)

1.333 (0.992–1.791)

Polymorphic VPC

1.256 (0.957–1.650)

1.179 (0.894–1.554)

VPC runs

2.196*** (1.518–3.180)

2.228*** (1.523–3.259)

N

1732

1732

1726

1727

1729

1720

Reduction of M/F HR compared to Model 1, %

 -

14.7

2.7

8.9

12.3

31.3

(B) All causes

Smoking

2.058**** (1.600–2.647)

2.059**** (1.593–2.662)

Obesity

1.001 (0.805–1.245)

1.071 (0.857–1.339)

Grade II hypertension

1.136 (0.913–1.412)

1.108 (0.887–1.385)

Total cholesterol

1.000 (0.809–1.236)

0.986 (0.796 – 1.221)

Triglycerides

0.897 (0.595–1.354)

0.944 (0.625 – 1.426)

Reported MI

1.208 (0.920–1.586)

1.132 (0.859–1.492)

Reported stroke

1.549** (1.162–2.065)

1.565** (1.172–2.092)

ST depression

1.461** (1.110–1.922)

1.427* (1.079–1.885)

VPC ≥ 10/h

1.131 (0.894–1.431)

1.100 (0.866–1.397)

Polymorphic VPC

1.283* (1.040–1.582)

1.225 (0.991–1.515)

VPC runs

1.904*** (1.400–2.592)

1.947*** (1.422–2.666)

N

1732

1732

1726

1727

1729

1720

Reduction of M/F HR compared to Model 1, %

-

11.9

0.4

5.0

9.1

22.2