| Model 1 | Model 2 | ||||
---|---|---|---|---|---|---|
HR | 95% CI | P | HR | 95% CI | P | |
(A) CVD | Â | Â | Â | Â | Â | Â |
Men | ||||||
 VPC ≥ 10/h | 1.537* | (1.110;2.129) |  < 0.05 | 1.402* | (1.006;1.954) |  < 0.05 |
 Polymorphic VPC | 1.477* | (1.079;2.023) |  < 0.05 | 1.496* | (1.082;2.066) |  < 0.05 |
 VPC runs | 2.614*** | (1.763;3.876) |  < 0.001 | 2.447*** | (1.626;3.683) |  < 0.001 |
 Women | ||||||
 VPC ≥ 10/h | 2.076** | (1.251;3.445) |  < 0.01 | 2.389** | (1.416;4.031) | 0.001 |
 Polymorphic VPC | 1.281 | (0.810;2.028) | 0.290 | 1.171 | (0.733;1.872) | 0.509 |
 VPC runs | 2.213 | (0.963;5.085) |  < 0.1 | 2.746* | (1.178;6.403) |  < 0.05 |
(B) All causes | Â | Â | Â | Â | Â | Â |
Men | ||||||
VPC ≥ 10/h | 1.272 | (0.976;1.658) |  < 0.1 | 1.197 | (0.915;1.566) | 0.189 |
Polymorphic VPC | 1.449** | (1.133;1.853) |  < 0.01 | 1.481** | (1.153;1.902) |  < 0.01 |
VPC runs | 2.177*** | (1.563;3.032) |  < 0.001 | 2.119*** | (1.508;2.977) |  < 0.001 |
Women | ||||||
VPC ≥ 10/h | 1.514 | (0.995;2.304) |  < 0.1 | 1.594* | (1.040;2.442) |  < 0.05 |
Polymorphic VPC | 1.228 | (0.866;1.743) | 0.250 | 1.107 | (0.771;1.589) | 0.582 |
VPC runs | 1.902 | (0.968;3.737) |  < 0.1 | 2.187* | (1.105;4.331) |  < 0.05 |