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Table 4 Univariate and multivariate analysis with underestimation of serum creatinine as the outcome variable

From: Hemodilution is associated with underestimation of serum creatinine in cardiac surgery patients: a retrospective analysis

Variable Univariate analysis Multivariate analysis
HR (95% CI) P value HR (95% CI) P value
Sex, Male 1.44 (1.12–1.85) 0.004   
BMI (per 1 kg/m2 increase) 1.01 (0.96–1.06) 0.723   
Age (per 1 unit increase) 1.05 (1.04–1.60) < 0.001 1.05 (1.01–1.10) 0.035
Hypertension (present) 1.81 (1.41–2.33) < 0.001   
Diabetes (present) 2.71 (1.93–3.81) < 0.001   
CKD (present) 2.10 (0.72–6.10) 0.172   
NYHA III-IV (present) 2.02 (1.56–2.61) < 0.001   
Preoperative SCr (per 1 μmol/L increase) 1.01 (1.01–1.02) < 0.001 1.05 (1.03–1.08) 0.000
LVEF (per 1 unit decrease) 1.02 (1.01–1.04) 0.010 1.10 (1.04–1.17) 0.001
Off-pump surgery (present) 5.35 (4.03–7.09) < 0.001   
CPB (per 1 min increase) 1.00 (1.00–1.01) 0.061   
Aortic cross-clamp (per 1 min increase) 1.01 (1.00–1.01) 0.014   
Oliguria (present) 1.87 (0.66–5.29) 0.239   
Cumulative fluid balance (per 1 L increase 1.00 (1.00–1.01) < 0.001 1.007 (1.005–1.009) 0.000