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Table 4 Multilevel multivariate models for PHYS and PSYS of CHF-PRO

From: Assessment of chronic disease self-management in patients with chronic heart failure based on the MCID of patient-reported outcomes by the multilevel model

Parameters Model 1 Model 2 Model 3
PHY PSY PHY PSY PHY PSY
Fixed effects   
Intercept 68.18 (0.26) 97.02 (0.25) 58.68 (0.51) 88.43 (0.64) 63.04 (1.74) 77.73 (1.77)
Time    4.16 (0.17)* 3.71 (0.19)* 2.27 (0.18)* 2.15 (0.21)*
Age      − 0.12 (0.01)* − 0.02 (0.01)*
Female      − 1.05 (0.40)* − 1.36 (0.36)*
NYHA      − 3.10 (0.23)* − 0.76 (0.22)*
CCI      − 0.43 (0.16)* − 0.30 (0.14)*
ACEI or ARB      − 0.42 (0.45) − 1.00 (0.40)*
Regular schedule      1.24 (0.22)* 1.46 (0.23)*
Low sodium diet      0.86 (0.19)* 0.76 (0.20)*
Avoid over-eating      1.96 (0.26)* 2.63 (0.28)*
Exercises      1.18 (0.14)* 0.55 (0.14)*
Random effects
Level 3 (subjects)
 (Intercept)   13.85 (2.35)   67.50 (9.42)*   68.25 (7.96)*
 (Intercept)   1.81 (1.85)   38.57 (8.90)*   49.07 (8.02)*
 (Intercept)   10.50 (2.29)   148.65 (13.84)*   159.18 (13.40)*
 (Time)     2.91 (1.01)*   4.47 (0.87)*
 (Time)     8.58 (1.27)*   10.90 (1.25)*
Level 2 (time point)
 (Intercept)   78.32 (2.99)   47.40 (2.19)*   34.55 (1.60)*
 (Intercept)   54.76 (2.65)   28.19 (1.77)*   17.02 (1.28)*
 (Intercept)   85.00 (3.24)   46.88 (2.12)*   36.62 (1.67)*
− 2 Log likelihood   27,286.37   26,155.51   25,458.50
  1. ACEI angiotensin converting enzyme inhibitors, ARB angiotensin receptor antagonist, CCI Charlson Comorbidity Index CHF-PRO chronic heart failure—patient reported outcome, NYHA New York Heart Association functional class, PHYS physical scores, PSYS psychological scores