Table 4 Clinical characteristics of young ACS patients according to homocysteine levels
Characteristics | HCY ≤ 15 µmol/L (n = 314) | HCY > 15 µmol/L (n = 514) | P |
|---|---|---|---|
Baseline characteristics | |||
Age (years) | 33 (30–34) | 32 (30–34) | 0.303 |
Male, n (%) | 295 (93.95) | 500 (97.28) | 0.026 |
Drinker, n (%) | 64 (20.38) | 84 (16.34) | 0.161 |
Traditional coronary risk factors | |||
BMI (kg/m2) | 28.38 ± 4.09 | 28.60 ± 4.95 | 0.553 |
Smoker, n (%) | 215 (68.47) | 357 (69.46) | 0.816 |
Hypertension, n (%) | 154 (49.04) | 248 (48.25) | 0.830 |
Diabetes mellitus, n (%) | 91 (28.98) | 71 (13.81) | < 0.001 |
Family history of CAD, n (%) | 41 (13.06) | 75 (14.59) | 0.606 |
Laboratory results | |||
TG (mmol/L) | 1.84 (1.26–3.06) | 1.94 (1.36–2.84) | 0.571 |
TC (mmol/L) | 4.80 ± 1.56 | 4.65 ± 1.69 | 0.213 |
HDL-C (mmol/L) | 0.91 ± 0.22 | 0.90 ± 0.20 | 0.729 |
LDL-C (mmol/L) | 3.06 ± 1.55 | 2.97 ± 1.52 | 0.386 |
CR (µmol/L) | 71.83 ± 13.30 | 76.16 ± 13.04 | < 0.001 |
eGFR (ml/min/1.73 m2) | 109.30 (96.80–126.00) | 104.70 (91.10–118.65) | 0.002 |
hs CRP (mg/L) | 3.10 (1.12–11.9) | 2.97 (0.98–11.77) | 0.818 |
UA (µmol/L) | 397.56 ± 89.78 | 417.65 ± 99.77 | 0.004 |
Clinical type of ACS | |||
STEMI, n (%) | 100 (31.85) | 201 (39.11) | 0.041 |
NSTEMI, n (%) | 73 (23.25) | 94 (18.29) | 0.090 |
UAP, n (%) | 141 (44.90) | 219 (42.61) | 0.563 |
CAG characters | |||
None | 25 (7.96) | 24 (4.67) | 0.068 |
Single-vessel, n (%) | 142 (45.22) | 209 (40.66) | 0.218 |
Double-vessel, n (%) | 71 (22.61) | 132 (25.68) | 0.360 |
Triple-vessel, n (%) | 76 (24.20) | 149 (28.99) | 0.147 |
Multi-vessel, n (%) | 147 (46.82) | 281 (54.67) | 0.036 |
Gensini Score | 30 (12–48) | 32 (16–62) | 0.043 |
Cardiac function | |||
LVEF | 60 (56–65) | 60 (52–65) | 0.01 |